Prof. Xujie Zhou, Peking University First Hospital, China
Xu-jie Zhou is an Associate Professor and Principal Investigator at Peking University First Hospital, specializing in nephrology and medical research. With over 20 years in clinical medicine, he has significantly contributed to the genetic, mechanistic, and therapeutic studies of kidney diseases. His research has led to the discovery of key genetic markers for IgA nephropathy and lupus, laying a foundation for precision medicine. As a respected academic and clinician, he has published over 70 high-impact papers, received prestigious awards, and actively mentors young researchers, making significant contributions to renal medicine and genetics.
Publication Profile
Google Scholar
Academic Background 🎓
Xu-jie Zhou earned his MD and BA in English from Wuhan University of Science & Technology (2006). He further pursued a PhD in Nephrology from Peking University Institute of Nephrology (2011). His medical education and bilingual proficiency have enabled him to excel in global research collaborations. His doctoral studies laid the groundwork for groundbreaking genetic discoveries in kidney disease. With extensive postdoctoral training, he has expanded his expertise in genetic and clinical nephrology, making significant contributions to medical education, translational research, and patient care worldwide.
Professional Experience 🏥
Xu-jie Zhou has progressed through various clinical and academic roles at Peking University First Hospital since 2011. Starting as a Resident Physician (2011-2016), he advanced to Assistant Professor (2011-2017), Attending Physician (2016-2020), Associate Researcher (2017-present), Associate Chief Physician (2020-present), and Associate Professor (2021-present). Throughout his career, he has combined clinical excellence, research innovation, and mentorship. His expertise spans nephrology, genetics, and medical education, shaping the future of kidney disease treatment. His leadership in genetic nephrology and translational medicine has earned him recognition in both academic and clinical circles.
Award and Honors 🏆
Xu-jie Zhou has received numerous prestigious awards, including the National Natural Science Foundation Outstanding Youth Fund (2021), Academy of Medical Sciences Newton Advanced Fellowship (2021), Beijing Youth Top-notch Talent (2018), and Outstanding Young Physician at Peking University (2024). He has also been honored with the “Respect for Life, Honor for Doctors” Award (2023), Peking University Medical Youth Science & Technology Award (2023), and National Outstanding PhD Dissertation Nomination (2013). His contributions to medical science and education have earned widespread recognition, positioning him as a leading researcher in nephrology.
Research Focus🔬
Xu-jie Zhou specializes in genetic nephrology, with a focus on IgA nephropathy, lupus, and hereditary kidney diseases. His research includes genome-wide association studies, discovering 21 new genes for IgA nephropathy and 10 for lupus. He has pioneered studies on autophagy pathways, proposing novel therapeutic strategies. His work emphasizes precision medicine, personalized treatment, and translational research. He has published extensively in top-tier journals, influencing global nephrology research. His innovations in machine learning, single-cell analysis, and pathway genetics have transformed the understanding and treatment of complex kidney diseases.
Publication Top Notes
1️⃣ Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 🧬
📅 Year: 2021 | 📑 Cited by: 13,586
2️⃣ Exploring the Role of Autophagy-Related Gene 5 (ATG5) Yields Important Insights Into Autophagy in Autoimmune/Autoinflammatory Diseases 🔍
📅 Year: 2018 | 📑 Cited by: 273
3️⃣ Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population 🧪
📅 Year: 2011 | 📑 Cited by: 271
4️⃣ High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry 🧫
📅 Year: 2016 | 📑 Cited by: 246
Conclusion
Xu-jie Zhou is a distinguished nephrologist and researcher with over 70 SCI publications in prestigious journals like Nature Genetics and Annals of the Rheumatic Diseases. His groundbreaking work in genome-wide association studies identified 21 new susceptibility genes for IgA nephropathy and 10 for lupus, significantly advancing nephrology research. He has received numerous accolades, including the National Natural Science Foundation–Outstanding Youth Foundation (2021) and the Outstanding Young Physician in Peking University (2024). As an associate editor, peer reviewer for 50+ journals, and mentor to young scholars, his contributions to research, education, and scientific leadership make him a strong candidate for the Best Researcher Award.