Prof Dr. Pelin Kelicen Uğur | Neuropharmacology | Best Researcher Award
Prof Dr E. PelinKelicen Uğur, Hacettepe University, Turkey
Prof. Dr. E. Pelin Kelicen Uğur is a distinguished pharmacologist at Hacettepe University in Turkey, with over two decades of teaching and research experience. She specializes in the pharmacology of neurodegenerative diseases and has made significant contributions to understanding the biochemical pathways involved in brain ischemia and diabetes. Dr. Kelicen is recognized for her impactful research and has published extensively in reputable journals, reflecting her commitment to advancing knowledge in pharmacology and neuropharmacology.
Publication profile
Academic Background
Prof. Dr. E. Pelin Kelicen Uğur completed her Bachelor of Pharmacy (B.Pharm) at Hacettepe University in 1996. She pursued her Master of Science (M.Sc.) in Pharmacology from the same institution, graduating in 1996 with a thesis focused on utilizing the mice air-pouch as a model for inflammation. Dr. Kelicen then attained her Doctorate (Ph.D.) in Pharmacology in 2001, with a thesis investigating the effects of a nitrone spin-trapping agent on Src and Erk activity in human neuroblastoma cells under the supervision of Prof. Eric Paulson.
Professional Experience
Prof. Kelicen has been a prominent faculty member at Hacettepe University since 2004, where she began as an Assistant Professor, progressing to Associate Professor (2005-2011), and currently serves as a Professor of Pharmacology (2011-present). In addition to her teaching responsibilities, she has been involved in various research roles, including a research fellow from 1994 to 2004. She has extensive experience in teaching both undergraduate and graduate courses in pharmacology, covering areas such as Central Nervous System Pharmacology, Endocrine System Pharmacology, and Cardiovascular System Pharmacology.
Research Focus
Prof. Kelicen’s research focuses on neurodegenerative diseases, ischemic and diabetic brain conditions, and the role of neurosteroids and autophagy pathways in Alzheimer’s disease. She employs various experimental techniques, including in vitro isolated organ baths, neuronal and glial cell culture, and in vivo studies utilizing transgenic models. Her work explores critical mechanisms such as aromatase and seladin-1 expression and the impact of transcription factors on neuropharmacological outcomes.
Publication Top Notes
Kelicen, P. and A. Nordberg, “Feedback regulation of SREBP and aromatase in A beta(25-35)-supplemented human neuroblastoma cells.” Cell. Mol. Neurobiol., 2006, 26(3): 225-235.
Kelicen, P., M. Cincioğlu, F. Hızlı, A. Nordberg, “Aβ25-35 attenuated SREBP level in nuclear extracts of serum-deprived human neuroblastoma cells.” Neurochem. Res., 2008, 34(5): 845-850.
Kose Selma, Cinar Elif, Akyel Hilal, Cakir Aktas Canan, Tel Banu Cahide, Karatas Hulya, Kelicen Uğur Pelin. “Cerliponase Alfa Decreases Aβ Load and Alters Autophagy-Related Pathways in mouse hippocampal neurons exposed to fAβ1-42.” Life Sciences, Available online 1 October 2024, 123105. https://doi.org/10.1016/j.lfs.2024.123105.
Yaşayan G, Nejati O, Ceylan AF, Karasu Ç, Kelicen-Ugur P, Bal-Öztürk A, Zarepour A, Zarrabi A, Mostafavi E. “Tackling chronic wound healing using nanomaterials: advancements, challenges, and future perspectives,” Applied Materials Today, 2023, 32, 101829, https://doi.org/10.1016/j.apmt.2023.101829.
Maleki A, Seyedhamzeh M, Yuan M, Agarwal T, Sharifi I, Mohammadi A, Kelicen-Uğur P, Hamidi M, Malaki M, Al Kheraif AA, Cheng Z, Lin J. “Titanium-Based Nanoarchitectures for Sonodynamic Therapy-Involved Multimodal Treatments.” Small, 2023, 19(12): e2206253.
Kartal Y, Tokat UM, Kelicen-Ugur P, Yılmaz S, Karahan S, Budak MT. “Evaluation of the Relationship Between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells.” Curr Mol Pharmacol., 2023, 16(6): 606-628.
Conclusion