mojtaba Mortazavi | Genetics and Molecular Biology | Best Researcher Award

mojtaba Mortazavi | Genetics and Molecular Biology | Best Researcher Award

Dr mojtaba Mortazavi, kerman university, Iran

Dr. Mojtaba Mortazavi, a distinguished biochemist, earned his B.S. in Biology (2000) and Ph.D. in Biochemistry (2011) from Tarbiat Modares University, Tehran, Iran. His research spans enzyme structure-function relationships, protein engineering, molecular docking, antimicrobial peptides, and biosensors. Dr. Mortazavi has contributed to notable projects, including stabilizing luciferase enzymes and screening β-lactamase-producing bacteria. He is a prolific author, with publications in Protein Engineering, Design & Selection and Current Pharmaceutical Biotechnology. His work on drought-responsive proteins and enzyme kinetics is widely recognized. Passionate about innovation, Dr. Mortazavi explores bioluminescence, bioinformatics, and pharmaceutical biotechnology. 🌟📚

Publication Profile

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Education

Dr. Mojtaba Mortazavi embarked on his academic journey with a High School Diploma from 12 Bahman High School, Jannat Shahr, Darab, Iran, in 1996 🎓. He earned his B.S. in Biology from Shahid Chamran University, Ahvaz, Iran, in 2000 🧪. Pursuing his passion for biochemistry, he completed his M.Sc. in Biochemistry at the College of Biological Sciences, Tarbiat Modares University, Tehran, Iran, in 2006 🧫. Dr. Mortazavi culminated his academic achievements with a Ph.D. in Biochemistry from the same university in 2011, specializing in advanced biochemical research and applications 🥼🔬.

Experience

Dr. Mojtaba Mortazavi is a leading expert in enzyme structure-function relationships and pharmaceutical biotechnology. His work spans molecular identification of β-lactamase-producing bacteria, antimicrobial peptides, and protein-protein interactions. Skilled in recombinant enzyme production, he applies advanced techniques like circular dichroism, fluorescence spectroscopy, and bioinformatics for structural characterization and molecular docking. Dr. Mortazavi excels in peptide engineering, cell culture, and biosensor development, alongside pioneering bioluminescence applications and drought-responsive protein identification in tea. With expertise in cloning, expression, and purification of enzymes, his research bridges biotechnology and pharmaceutical innovation, fostering advancements in nano alumina evaluations and rare codon analysis. 🌱✨

Research Projects

Dr. Mojtaba Mortazavi has contributed significantly to various groundbreaking research areas. His work includes the cloning and characterization of firefly luciferase from a new lampyroid species 🔥, exploring extended-spectrum β-lactamase-producing bacteria from clinical specimens 🦠, and the stabilization of luciferase enzyme using site-directed mutagenesis 🧬. Additionally, Dr. Mortazavi led the internal evaluation of the Research Department of Biotechnology at the Institute of Science and High Technology and Environmental Sciences 🏫. These studies reflect his commitment to advancing biotechnology and microbial research.

Research Focus

Dr. Mojtaba Mortazavi’s research spans multiple domains, primarily focusing on protein engineering, biocatalysis, and biochemical analysis. His work includes the design of thermostable luciferases, catalytic nanocomposites, and studies on the Pichia pastoris expression system for protein production. He also investigates the effects of ionic liquids on enzyme structure and activity. His interdisciplinary approach also touches on biotechnology, molecular dynamics, and drug design. Key areas of his expertise include biocatalysis, nanocomposites, biochemical systems, and enzymology. 🧬🔬⚙️🌱

Publication top Notes

Design of thermostable luciferases through arginine saturation in solvent-exposed loops

New developments in Pichia pastoris expression system, review and update

Synthesis and characterization of GO/ZIF-67 nanocomposite: investigation of catalytic activity for the determination of epinine in the presence of dobutamine

The effect of different percentages of triethanolammonium butyrate ionic liquid on the structure and activity of urate oxidase: Molecular docking, molecular dynamics simulation …

cDNA cloning, expression and homology modeling of a luciferase from the firefly Lampyroidea maculata

Design, synthesis and biological assessment of acridine derivatives containing 1, 3, 4-thiadiazole moiety as novel selective acetylcholinesterase inhibitors

Evaluation of tea (Camellia sinensis L.) biochemical traits in normal and drought stress conditions to identify drought tolerant clones

Spectroscopic and functional characterization of Lampyris turkestanicus luciferase: a comparative study

Enhancement of Thermostability of Aspergillus flavus Urate Oxidase by Immobilization on the Ni-Based Magnetic Metal–Organic Framework

Surface charge modification increases firefly luciferase rigidity without alteration in bioluminescence spectra

Effects of 940 MHz EMF on luciferase solution: Structure, function, and dielectric studies

Shahrzad manavi nameghi | Molecular genetics | Women Researcher Award

Ms. Shahrzad manavi nameghi | Molecular genetics | Women Researcher Award

Ms. Shahrzad manavi nameghi, Islamic Azad Tehran University of Medical Science, Iran

Ms. Shahrzad Manavi Nameghi: A Suitable Candidate for the Research for Women Researcher Award

Publication profile

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Education

Ms. Shahrzad Manavi Nameghi holds an M.Sc. in Molecular Biology-Genetics from Islamic Azad Tehran University of Medical Sciences, Tehran, Iran (2017–2019), where her thesis focused on the relation between rs1800437 GIPR gene and the risk of type 2 diabetes. She also earned a B.Sc. in Cellular and Molecular Biology-Genetics from Shahid Bahonar University, Kerman, Iran (2013–2017).

Work Experience and Mentorship

She has worked as a peer reviewer for the Journal of Regenerative Biology and Medicine (2020–2022) and as a main lab technician in the molecular section at Mendel Medical Genetics Laboratory, Tehran, Iran (2020–2023). Additionally, she has experience teaching biology and Arabic for college entrance exam preparation at Payandegan Science Institute (2017-2019).

Technical Skills

Her technical proficiency includes programming and software tools like R, NGS Analysis, Gene Marker, and Gene Runner. She is proficient in Microsoft Office and has strong language skills in English (IELTS 6.5) and basic German (A2.1).

Certificates and Workshops

Ms. Nameghi has participated in numerous workshops and conferences, including those focused on laboratory animals, miRNA/siRNA primer design, and essential lab skills in molecular biology.

Conclusion

Ms. Shahrzad Manavi Nameghi’s strong academic background, extensive research contributions, and practical laboratory experience make her a highly suitable candidate for the Research for Women Researcher Award. Her dedication to advancing knowledge in molecular biology and genetics, particularly in the context of diabetes and cancer research, exemplifies the qualities recognized by this award.

Hyunsook Lee | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Prof Dr Hyunsook Lee | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Professor, Head of SNU AI-Bio Research Center,Seoul National University/College of Natural Sciences/Dept. of Biological Sciences, South Korea 

Dr. Hyunsook Lee is a distinguished professor in the Department of Biological Sciences and the Institute of Molecular Biology and Genetics at Seoul National University (SNU) 👩‍🔬📚. As the Head of the AI-Bio Research Center at SNU 🧠🔬, she is a leading figure in integrating artificial intelligence with molecular biology to advance personalized medicine and cancer research 🧬🤖. Dr. Lee holds a Ph.D. from the University of Cambridge, where her research on cell cycle checkpoints and the BRCA2 gene significantly contributed to our understanding of breast cancer 🔬. She has held esteemed positions at Harvard Medical School and the University of Washington during her postdoctoral studies and has received numerous awards, including the Wellcome Trust International Prize and the POSCO Chungam Science Award 🏆. Beyond her research, Dr. Lee serves on multiple advisory committees for the Korean government and various scientific organizations 📈🏛️. Her dedication to science, education, and innovative research has established her as a highly respected leader in her field 🌟.

Publication profile

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Education

Dr. Hyunsook Lee 🎓 embarked on her academic journey with a Bachelor’s degree in Biology from Ewha Womans University (1986. Mar – 1990. Feb) 🏫. She then pursued a Master’s degree in Biology at Seoul National University (1990. Mar -1992. Feb) 🎓. Her passion for molecular biology led her to the University of Cambridge in the UK, where she earned her Ph.D. (1996. Oct – 1999. Sept) 🇬🇧. Her doctoral research focused on “Cell cycle checkpoints and the breast cancer susceptibility gene, Brca2” 📖, under the supervision of Prof. Ashok Venkitaraman and Dr. Michael Neuberger, FRS. Her thesis was examined by Sir Tim Hunt, a Nobel Laureate (2001), and Prof. Jonathan Pines 🧬. Following her Ph.D., she received the Wellcome Trust Postdoctoral Fellowship (Wellcome Trust International Prize) 🏆, working with Prof. Frank McKeon at Harvard Medical School (2000. Jan ~ 2000. Aug) 🏥 and Prof. David Kimelman at the University of Washington, Seattle (2000. Aug ~ 2002. Sept) 🧫.

Professional Experience

Dr. Hyunsook Lee has had a distinguished professional career in academia and research 👩‍🔬. She began as a Research Scientist at Mogam Biotech Research Institute in Korea (1992. Mar – 1994. May) 🔬 and was promoted to Senior Research Scientist (1994. May – 1996. Aug) 🧬. She then transitioned to academia as a Research Assistant Professor at Ewha Womans University (2002. Sept – 2003) 🧪. In 2004, she joined the Dept. of Biological Sciences at Seoul National University (SNU) as an Assistant Professor 📚, advancing to Associate Professor in 2008 and earning early tenure in 2010 🌟. By 2012, she became a full Professor at SNU 🌍. Dr. Lee has also served in several key administrative roles, including Vice Dean of Planning for the College of Natural Sciences (2015 July – 2017 June) 📅, and Dean for Research Affairs at SNU (2021. Feb – 2023. Feb) 🎓. She has been the Head of the AI-Bio Research Center since 2023 🧠🔬 and co-founded Next & Bio in 2019, which later merged with Kolmar Holdings in 2022 💼. Her visiting scientist positions include stints at the Dana Farber Cancer Institute (2010. Aug – 2011. July) 🧬 and Samsung Advanced Institute of Technology (2020. Aug – 2021. Feb) 🏥.

Certificates

Dr. Hyunsook Lee holds prestigious certificates including the Wellcome Trust International Prize for her postdoctoral fellowship 🏆, and recognition from the POSCO Bessemer Science Fellowship and POSCO Chungam Science Award 🏅. Her expertise and contributions to molecular biology and cancer research have been widely acknowledged through these esteemed honors 🎖️.

Research Interest

Dr. Hyunsook Lee’s research interests are centered on the intersection of molecular biology, cancer research, and artificial intelligence 🧬🤖. She is particularly focused on cell cycle checkpoints and the roles of genes such as BRCA2 in breast cancer susceptibility 🔬. Her work aims to elucidate the molecular mechanisms underlying cancer development and progression, with the ultimate goal of identifying new therapeutic targets and strategies for cancer treatment 🏥. Additionally, as the Head of the AI-Bio Research Center at Seoul National University 🧠🔬, Dr. Lee is at the forefront of integrating AI technologies with biological research to advance personalized medicine and enhance predictive models for disease outcomes 📈. Her innovative approach combines traditional molecular biology with cutting-edge AI, striving to push the boundaries of what is possible in biomedical research and healthcare innovation 🌟.

Award and Honor

Dr. Hyunsook Lee has been the recipient of numerous prestigious awards and honors throughout her illustrious career 🎖️. She was awarded the Wellcome Trust International Prize for her postdoctoral fellowship, recognizing her outstanding contributions to molecular biology 🏆. Her groundbreaking research has earned her accolades from various scientific organizations, including the POSCO Chungam Science Award and the POSCO Bessemer Science Fellowship 🏅. In 2021, she was appointed to several high-profile advisory committees, such as the Advisor Committee for STEPI, the Ministry of Education, and the Ministry of SMEs & Startups in Korea 📈🏫. Additionally, Dr. Lee has been honored with leadership roles, including her tenure as Dean for Research Affairs at Seoul National University and her current position as Head of the AI-Bio Research Center 🧠🔬. Her contributions to science and education have made her a highly respected figure in the academic and research communities 🌟.

Research Skill

Dr. Hyunsook Lee possesses a diverse and robust skill set in research, particularly in molecular biology, cancer biology, and the application of artificial intelligence in biomedical research 🧬🤖. She is adept in techniques such as cell cycle analysis, gene cloning, and protein expression and purification 🔬. Her expertise extends to advanced genomic technologies, including CRISPR-Cas9 gene editing and next-generation sequencing (NGS) 🧫. Dr. Lee is also skilled in bioinformatics and computational biology, employing AI and machine learning algorithms to analyze complex biological data and develop predictive models for disease outcomes 📊. Her proficiency in these areas enables her to conduct cutting-edge research that bridges traditional experimental biology with modern computational approaches, driving forward innovative solutions in cancer treatment and personalized medicine 🏥🌟.

Publications

  • Kim, H., Jang, J., Choi, J.H., … Lee, J.K., Park, J.K.
    • Title: Establishment of a patient-specific avatar organoid model derived from EUS-guided fine-needle biopsy for timely clinical application in pancreatic ductal adenocarcinoma (with video)
    • Journal: Gastrointestinal Endoscopy, 2024
    • Volume: 100
    • Issue: 1
    • Pages: 85–96.e9
  • Lee, J.J., Kim, H., Park, H., … Han, W., Lee, H.
    • Title: Disruption of G-quadruplex dynamicity by BRCA2 abrogation instigates phase separation and break-induced replication at telomeres
    • Journal: Nucleic Acids Research, 2024
    • Volume: 52
    • Issue: 10
    • Pages: 5756–5773
  • Youk, J., Kwon, H.W., Lim, J., … Son, T.G., Ju, Y.S.
    • Title: Quantitative and qualitative mutational impact of ionizing radiation on normal cells
    • Journal: Cell Genomics, 2024
    • Volume: 4
    • Issue: 2
    • Article: 100499
  • Koh, Y., Kim, H., Joo, S.Y., … Yoon, S.-S., Park, J.K.
    • Title: Genetic assessment of pathogenic germline alterations in lysosomal genes among Asian patients with pancreatic ductal adenocarcinoma
    • Journal: Journal of Translational Medicine, 2023
    • Volume: 21
    • Issue: 1
    • Page: 730
  • Lee, J., Sung, K., Joo, S.Y., … Kim, S.K., Lee, H.
    • Title: Dynamic interaction of BRCA2 with telomeric G-quadruplexes underlies telomere replication homeostasis
    • Journal: Nature Communications, 2022
    • Volume: 13
    • Issue: 1
    • Page: 3396
  • Kim, Y., Park, J., Joo, S.Y., … Lee, H., Cho, Y.
    • Title: Structure of the Human TELO2-TTI1-TTI2 Complex
    • Journal: Journal of Molecular Biology, 2022
    • Volume: 434
    • Issue: 2
    • Page: 167370
  • Park, J., Yeu, S.Y., Paik, S., … Koh, Y., Lee, H.
    • Title: Loss of BubR1 acetylation provokes replication stress and leads to complex chromosomal rearrangements
    • Journal: FEBS Journal, 2021
    • Volume: 288
    • Issue: 20
    • Pages: 5925–5942
  • The, F., Lee, H.
    • Title: Editor Profile: Hyunsook Lee
    • Journal: FEBS Journal, 2021
    • Volume: 288
    • Issue: 15
    • Pages: 4439–4441
  • Lee, J.J., Lee, J., Lee, H.
    • Title: Alternative paths to telomere elongation
    • Journal: Seminars in Cell and Developmental Biology, 2021
    • Volume: 113
    • Pages: 88–96
  • Ma, X., Song, S., Kim, S., … Park, W., Sim, S.J.
    • Title: Single gold-bridged nanoprobes for identification of single point DNA mutations
    • Journal: Nature Communications, 2019
    • Volume: 10
    • Issue: 1
    • Page: 836

Ramin Saravani | Genetic Association Study Award | Young Scientist Award

Dr. Ramin Saravani | Genetic Association Study Award | Young Scientist Award

Dr. Ramin Saravani, Zahedan University of Medical Sciences, Iran

Dr. Ramin Saravani is a highly accomplished researcher and educator in clinical biochemistry, currently serving as a Full-time Research Assistant at Zahedan University of Medical Sciences. With a Ph.D. from Shahid Sadoughi University of Medical Sciences, he excels in PCR, ELISA, and diverse molecular techniques. Recognized as a top young biochemistry researcher, he has received prestigious awards including the “Dr. Shahryari” award and “Dr. Kazemi Ashtiani Prize” research grant. Dr. Saravani’s expertise spans from teaching biochemistry with clarity to pioneering research in molecular biology, earning him global recognition as one of the top 2% scientists worldwide. 🎓🔬

 

Publication Profile

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Education

Dr. Ramin Saravani embarked on his academic journey with a Bachelor of Science in Cellular and Molecular Biology from the University of Sistan and Balouchestan, showcasing his early commitment to the biological sciences. Building upon this foundation, he pursued a Master of Science in Clinical Biochemistry at Ferdowsi University of Mashhad, excelling with a perfect GPA. His academic prowess culminated in a Doctor of Philosophy in Clinical Biochemistry from Shahid Sadoughi University of Medical Sciences, where he maintained another perfect GPA. 📚 Throughout his educational endeavors, Dr. Saravani demonstrated a relentless pursuit of knowledge and a passion for understanding the intricacies of biochemical processes.

 

Experience

Dr. Ramin Saravani has contributed significantly to academia and research, serving as a Full-time Research Assistant at Zahedan University of Medical Sciences since April 2019. In this role, he continues to delve into the complexities of biochemistry, pushing the boundaries of scientific understanding. Prior to this, from September 2015 to March 2017, he shared his expertise as an Invited Lecturer at the Zahedan Branch of Islamic Azad University. 🎓 Through his lectures, Dr. Saravani not only disseminated knowledge but also inspired the next generation of scientists. His dual roles reflect his dedication to both advancing research and nurturing budding minds in the field of biochemistry.

 

Awards

Dr. Ramin Saravani has garnered esteemed recognition for his groundbreaking contributions to medical research, earning prestigious awards and grants. In 2022, he was honored with the esteemed “Dr. Shahryari” award by Iran’s National Elites Foundation, highlighting his excellence as a Young Research Assistant. Continuing his trajectory of success, Dr. Saravani was bestowed with the distinguished “Dr. Kazemi Ashtiani Prize” research grant in 2024, a testament to his exceptional achievements as a Young Scientist. Additionally, he received the early career research grant from the National Institute for Medical Research Development in the same year, underscoring his status as a promising researcher in the field. 🏅

 

Research Focus

Dr. Ramin Saravani’s research focus lies at the intersection of nanotechnology and medical science. 🧬 His extensive work encompasses the development and application of nanomaterials and nanoparticles in various aspects of biomedical research, including cancer therapy, diagnosis, and drug delivery systems. His contributions span a wide range of topics, from the synthesis and characterization of novel nanomaterials to their effectiveness in treating specific diseases such as breast carcinoma and inflammatory bowel disease. Through his innovative research endeavors, Dr. Saravani is paving the way for advancements in nanomedicine, offering promising solutions for tackling complex medical challenges.