Prof at QUT,Ā Australia
Professor Lyn Griffiths is a prominent molecular geneticist and Director of the Centre for Genomics and Personalised Health at Queensland University of Technology (QUT), Australia. Her research focuses on identifying genes associated with common traits and disorders, including migraine, cardiovascular diseases, memory, dementia, and concussion. With over 440 peer-reviewed publications, she has made significant contributions to neurovascular disorder diagnostics, such as familial migraine and hereditary stroke. Professor Griffiths has established valuable population genomics resources and leads innovative projects like the Defence Innovation Hub, utilizing next-generation DNA technology for identifying missing servicemen.
Publication Profile
Scopus
Orcid
Education š
Professor Griffiths earned her Ph.D. in Molecular Genetics from the University of Queensland, Australia, where she developed a strong foundation in genetics research. Her academic journey has equipped her with extensive knowledge and skills in molecular biology, genetics, and bioinformatics. Throughout her education, she focused on understanding genetic influences on human health, which laid the groundwork for her future research in genomics and personalized medicine.
Experienceš¼
With years of research experience, Professor Griffiths has led numerous projects focusing on genetic disorders and disease diagnosis. As Director of the Centre for Genomics and Personalised Health at QUT, she oversees a diverse team of researchers dedicated to advancing genomics science. Her leadership has fostered collaborations with various institutions, enhancing research capabilities and training future genomics scientists. Additionally, her involvement in the Defence Innovation Hub illustrates her commitment to applying genetics research for real-world applications, including identifying the remains of missing servicemen.
Awards and Honors š
Professor Griffiths has received multiple accolades for her contributions to genetics research and personalized medicine. Her work has garnered significant competitive and industry research funding, enabling her to support a dynamic research team. She has been recognized for her innovative approaches to neurovascular disorder diagnostics and her leadership in establishing population genomics resources. Her dedication to advancing genomics and training future scientists continues to earn her respect and recognition in the scientific community.
Research Focus š¬
Professor Griffiths’ research primarily focuses on identifying genetic factors related to common traits and disorders, particularly in neurovascular health. Her work includes studying migraine, cardiovascular diseases, and dementia, aiming to enhance diagnostic methods and develop targeted treatments based on genetic information. She has established a significant population genomics bank, especially involving chronic kidney disease studies in the Norfolk Island cohort. By integrating next-generation sequencing data and innovative bioinformatics approaches, her research contributes to a deeper understanding of complex genetic conditions and their underlying pathways.
Conclusion š
Professor Lyn Griffiths and her research team, including PhD candidate Mohammed Alfayyadh, exemplify excellence in the field of genomics and personalized health. Their innovative work, particularly the development of the PathVar algorithm for variant calling in hemiplegic migraine, highlights their commitment to uncovering the genetic foundations of complex diseases. With their impressive publication record and the establishment of valuable genomic resources, they are strong contenders for the Best Researcher Award. Enhancing industry collaborations and focusing on translational research will further strengthen their impact and recognition in the scientific community.
Publication Top Notes
- Association Study of a Comprehensive Panel of Neuropeptide-Related Polymorphisms Suggest Potential Roles in Verbal Learning and Memory
- Associations between Cerebrovascular Function and the Expression of Genes Related to Endothelial Function in Hormonal Migraine
- Clinical and Neuroradiological Spectrum of Biallelic Variants in NOTCH3
- CpG Methylation Changes in Human Mesenchymal and Neural Stem Cells in Response to In Vitro Niche Modifications
- Epigenetic Regulation in Schizophrenia: Focus on Methylation and Histone Modifications in Human Studies
- Exercise is Associated with Younger Methylome and Transcriptome Profiles in Human Skeletal Muscle
- Fine-Mapping a Genome-Wide Meta-Analysis of 98,374 Migraine Cases Identifies 181 Sets of Candidate Causal Variants
- Genetic Causal Relationship Between Immune Diseases and Migraine: A Mendelian Randomization Study
- Genetics of Migraine: Complexity, Implications, and Potential Clinical Applications
- HMG-CoA Reductase is a Potential Therapeutic Target for Migraine: A Mendelian Randomization Study