Dr. Melese Hailu Legese, College of Health Sciences, Addis Ababa University and Department of Biochemistry and Microbiology, Uppsala University, Ethiopia
Dr. Melese Hailu Legese is a dedicated researcher and academician affiliated with Addis Ababa University and Uppsala University. He holds a BSc in Medical Laboratory Sciences (2007) and an MSc in Diagnostic and Public Health Microbiology (2014). He completed his PhD in 2022, focusing on the genomic epidemiology of antibiotic-resistant Enterobacteriaceae in sepsis patients. Dr. Legese has authored 17 publications and collaborated with global research groups, including KlebNET-GSP and LSHTM. His work addresses antimicrobial resistance (AMR), sepsis pathogens, and genomic surveillance systems, contributing to global health. He is a member of multiple esteemed microbiology societies. ✨📚
Publication Profile
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Academic and Professional Background 🎓🔬🌍
Dr. Melese Hailu Legese is a distinguished academic and researcher affiliated with Addis Ababa University and Uppsala University. He earned his BSc in Medical Laboratory Sciences from the University of Gondar (2007) and an MSc in Diagnostic and Public Health Microbiology from Addis Ababa University (2014). From 2017 to 2022, he pursued his PhD at Addis Ababa University, simultaneously serving as a guest doctoral researcher at Uppsala University since 2020. His research, focusing on the genomic epidemiology of antibiotic-resistant Enterobacteriaceae in sepsis patients using whole-genome sequencing, has culminated in impactful publications, international presentations, and global scientific collaborations. ✨📊🌐
Research Focus
Dr. Melese Hailu Legese’s research focuses on the genomic analysis of sepsis pathogens and antimicrobial resistance (AMR). Leveraging cutting-edge whole-genome sequencing (WGS), he investigates the genetic mechanisms driving AMR, including resistance genes, virulence factors, and pathogen evolution. His work also encompasses the study of emerging sepsis pathogens, integrating genomic, clinical, and epidemiological data to enhance diagnostic accuracy and develop targeted antimicrobial stewardship strategies. Dr. Legese’s research addresses critical challenges in infection control and AMR, contributing significantly to global efforts in combating resistant infections, particularly in resource-limited settings. 🌍🔬📊
Publication Top Notes
- Genomic characterizations of Klebsiella variicola: Emerging pathogens identified from sepsis patients in Ethiopian referral hospitals 🧬 (2025) – DOI: 10.1080/22221751.2024.2440494
- Sepsis: Emerging pathogens and antimicrobial resistance in Ethiopian referral hospitals 🦠 (2022) – DOI: 10.1186/s13756-022-01122-x
- Genomic Epidemiology of Carbapenemase-Producing and Colistin-Resistant Enterobacteriaceae among Sepsis Patients in Ethiopia: A Whole-Genome Analysis 🧪 (2022) – DOI: 10.1128/aac.00534-22
- Molecular Epidemiology of Extended-Spectrum Beta-Lactamase and AmpC Producing Enterobacteriaceae among Sepsis Patients in Ethiopia 🧬 (2022) – DOI: 10.3390/antibiotics11020131
- Multidrug-Resistant and Carbapenemase-Producing Enterobacteriaceae in Addis Ababa, Ethiopia 🦠 (2021) – DOI: 10.1155/2021/9999638
- Extended-Spectrum Beta-Lactamase and AmpC Beta-Lactamase Producing Gram-Negative Bacilli in Addis Ababa 🧪 (2020) – DOI: 10.1371/journal.pone.0241984
- Prevalence and Associated Risk Factors for Hepatitis B and C Viruses among Refugees in Gambella, Ethiopia 🩺 (2020) – DOI: 10.1186/s12889-020-08893-1
- Extended-Spectrum Beta-Lactamase Production and Multidrug Resistance in Addis Ababa 🦠 (2019) – DOI: 10.1186/s13756-019-0488-4
- Common Uropathogens and Antibiotic Susceptibility Patterns among Diabetic Patients 🧪 (2019) – DOI: 10.1186/s12879-018-3669-5
- Prevalence of Intestinal Parasites among River Water Contact Individuals in Ethiopia 🌊 (2018) – DOI: 10.1371/journal.pone.0204259
- Bacterial Profiles and Antimicrobial Resistance Patterns in Addis Ababa Hospitals 🩺 (2017) – DOI: 10.4172/0974-8369.1000408
- Multidrug-Resistant Bacteria in Postoperative Wound Infections in Addis Ababa 🩹 (2017) – DOI: 10.21767/1989-5216.1000233
- Patient Satisfaction with Clinical Laboratory Services in Addis Ababa 😊 (2017) – DOI: 10.2147/ppa.s132397
- Quality Assessment of Public Swimming Pools in Addis Ababa, Ethiopia 🌊 (2017) – DOI: 10.2174/1874285801711010098