Assist Prof Dr. Chen Huang | Bioinformatics | Best Researcher Award

Assist Prof Dr. Chen Huang | Bioinformatics | Best Researcher Award

Assist Prof Dr. Chen Huang, Macau University of Science and Technology, Macau

Assist. Prof. Dr. Chen Huang is a distinguished researcher in the field of bioinformatics, known for his groundbreaking work in computational biology and data analysis. He currently serves as an Assistant Professor at a leading university, where he combines his expertise in computer science and molecular biology to advance research in genomics and personalized medicine. Dr. Huang has been recognized for his innovative approaches to solving complex biological problems, earning him the prestigious Best Researcher Award. His contributions have significantly impacted the understanding of genetic data and the development of novel bioinformatics tools, making him a leader in his field

Publication profile

Academic Qualification

Assist. Prof. Dr. Chen Huang holds a Ph.D. in Biomedical Sciences with a specialization in Bioinformatics from the Institute of Chinese Medical Sciences at the University of Macau, China (2012-2017). He also earned an M.E. in Bioinformatics from the Biological Information Science and Technology Institute at Harbin Medical University, China (2007-2010). Dr. Huang began his academic journey with a B.S. in Biotechnology, focusing on Biopharmaceuticals, from the College of Life Science at Nanchang University, China (2003-2007). His diverse educational background has laid a strong foundation for his pioneering research in bioinformatics.

Working Experiances

Assist. Prof. Dr. Chen Huang is currently serving as an Assistant Professor at the State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macao, a position he has held since 2020. Prior to this role, he completed a post-doctoral fellowship at the Faculty of Health Sciences, University of Macau, Macao, from 2017 to 2020. Before his post-doctoral tenure, Dr. Huang worked as an Analyst at the Beijing Genomics Institute in Shenzhen (BGI-Shenzhen) from 2010 to 2012.

Publication Top Notes

Lu, C., Huang, C., Qu, S., Lin, H., Zhong, H.-J., & Chong, C.-M. (2024). Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2024.116379

Yang, X., Wu, Y., Chen, X., Qiu, J., & Huang, C. (2024). The transcriptional landscape of immune-response 3′-UTR alternative polyadenylation in melanoma. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms25053041

Zhang, Y.-Z., Lai, H.-L., Huang, C., Jiang, Z.-B., Yan, H.-X., Wang, X.-R., Xie, C., Huang, J.-M., Ren, W.-K., Li, J.-X., Zhai, Z.-R., Yao, X.-J., Wu, Q.-B., & Leung, E. L.-H. (2024). Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer. Phytomedicine. https://doi.org/10.1016/j.phymed.2024.155431

Cheng, X., Deng, M., Wang, Z., & Huang, C. (2024). MMP3C: An in-silico framework to depict cancer metabolic plasticity using gene expression profiles. Briefings in Bioinformatics. https://doi.org/10.1093/bib/bbad471

Wang, Z., Chen, X., Si, W., & Huang, C. (2023). Systemic pharmacology and bioinformatics: Exploring the modern biological mechanisms of rhubarb in the treatment of papillary thyroid carcinoma. MedComm – Future Medicine. https://doi.org/10.1002/mef2.69

Huang, C., Deng, M., Leng, D., Sun, B., Zheng, P., & Zhang, X. D. (2023). MIRS: An AI scoring system for predicting the prognosis and therapy of breast cancer. iScience. https://doi.org/10.1016/j.isci.2023.108322

Feng, Y., Chen, X., Zhang, X. D., & Huang, C. (2023). Metabolic pathway pairwise-based signature as a potential non-invasive diagnostic marker in Alzheimer’s disease patients. Genes. https://doi.org/10.3390/genes14061285

Cheng, T., Wu, Y., Liu, Z., Yu, Y., Sun, S., Guo, M., Sun, B., & Huang, C. (2022). CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2022.970950

Wu, L., Hou, X., Luo, W., Hu, H., Zheng, X., Chen, Y., Cheng, Z., Huang, C., & Sun, B. (2022). Three patterns of sensitization to mugwort, timothy, birch, and their major allergen components revealed by latent class analysis. Molecular Immunology. https://doi.org/10.1016/j.molimm.2022.03.009

Cheng, T., Chen, P., Chen, J., Deng, Y., & Huang, C. (2022). Landscape analysis of matrix metalloproteinases unveils key prognostic markers for patients with breast cancer. Frontiers in Genetics. https://doi.org/10.3389/fgene.2021.809600

Yue Gao | Bioinformatics Award | Best Researcher Award

Ms. Yue Gao | Bioinformatics Award | Best ReBioinformatics Awardsearcher Award

Ms. Yue Gao, Qufu Normal University, China

Assessment of Ms. Yue Gao for the Best Researcher Award

Publication profile

Scopus

Educational Background and Current Pursuits

Ms. Yue Gao is currently pursuing her master’s degree at the School of Computer Science, Qufu Normal University, Rizhao, China, after obtaining her B.S. degree from the same institution in 2023. Her academic trajectory shows a strong foundation in computer science, which is crucial for her research areas of interest. Her current focus is on pattern recognition and bioinformatics, fields that are highly relevant and evolving rapidly in today’s scientific landscape. This educational background provides a solid base for her ongoing research efforts.

 

Research Contributions in Spatially Resolved Transcriptomics Data Analysis

Ms. Gao’s work, as evidenced by her co-authorship in the paper titled “A Review of Recent Advances in Spatially Resolved Transcriptomics Data Analysis,” published in Neurocomputing in 2024, reflects her engagement with cutting-edge topics in bioinformatics. The paper contributes to the growing body of knowledge in transcriptomics, a field critical for understanding gene expression in a spatial context. Although this publication has not yet garnered citations, it demonstrates her ability to collaborate on significant scientific reviews, laying the groundwork for future impact in this domain.

Innovative Approaches in Pattern Recognition

In her conference paper “Spatial Domain Identification Based on Graph Attention Denoising Auto-encoder,” published in the Lecture Notes in Computer Science series in 2023, Ms. Gao explores advanced methodologies in pattern recognition. The use of a Graph Attention Denoising Auto-encoder represents a novel approach to spatial domain identification, highlighting her innovative contributions to the field. The paper has received one citation, indicating initial recognition of her work within the academic community.

Publication Top Notes

A review of recent advances in spatially resolved transcriptomics data analysis

Spatial Domain Identification Based on Graph Attention Denoising Auto-encoder

Conclusion

Ms. Yue Gao exhibits promising potential as a researcher, particularly in the areas of pattern recognition and bioinformatics. Her contributions to these fields, while still in the early stages, are grounded in robust academic training and demonstrate innovative thinking. Although her work is just beginning to gain traction in terms of citations, her research outputs align with the criteria for the Best Researcher Award. However, given the competitive nature of such awards, further recognition through citations and continued publication of impactful research would strengthen her candidacy.

 

Genetics and Molecular Biology

Introduction of Genetics and Molecular Biology

Genetics and Molecular Biology are at the forefront of understanding the intricate machinery that governs life itself. This dynamic field investigates the genetic material and molecular processes underlying inheritance, development, evolution, and the molecular mechanisms of diseases. It is a cornerstone of modern biological research and holds the promise of unlocking the secrets of life’s blueprint.

Genome Sequencing and Analysis:

The study of entire genomes, from humans to microbes, has revolutionized our understanding of genetics. Researchers in this subfield explore the structure and function of genes, regulatory elements, and the role of non-coding DNA.

Genetic Variation and Population Genetics:

Investigating how genetic variations occur within populations and evolve over time is essential for understanding the diversity of life. This subtopic delves into the mechanisms of genetic diversity, adaptation, and speciation.

Epigenetics:

Epigenetics explores changes in gene expression that do not involve alterations to the DNA sequence itself. Researchers study how factors like DNA methylation and histone modification influence gene regulation, development, and disease.

Molecular Mechanisms of Disease:

In this subfield, scientists investigate the molecular basis of genetic disorders and diseases, from cancer to rare genetic conditions. Understanding the underlying mechanisms is crucial for developing targeted therapies.

Synthetic Biology:

Synthetic biology involves the design and construction of artificial biological systems for diverse applications, such as biofuel production or medical treatments. Researchers engineer biological components to create new functions and capabilities.

Introduction of Agricultural and Biological Sciences Agricultural and Biological Sciences research plays a pivotal role in addressing the multifaceted challenges of our ever-evolving world. This field encompasses a wide array
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Introduction of Biochemistry Biochemistry is a captivating scientific discipline that delves into the intricate world of molecules and processes within living organisms. It serves as the bridge between biology and
Introduction of Genetics and Molecular Biology Genetics and Molecular Biology are at the forefront of understanding the intricate machinery that governs life itself. This dynamic field investigates the genetic material
Introduction of Business Business research is the driving force behind informed decision-making in the corporate world. It encompasses an array of methodologies and disciplines that aim to understand and improve
Introduction of Management and Accounting Management and Accounting research is the backbone of effective decision-making in organizations, spanning from the corporate world to the public sector. It encompasses the systematic
Introduction of Chemical Engineering   Chemical Engineering research plays a pivotal role in transforming raw materials into valuable products, advancing environmental sustainability, and developing innovative solutions across various industries. It
Introduction of Chemistry    Chemistry research lies at the heart of our understanding of matter and its interactions, and it's a cornerstone of scientific progress. Researchers in this dynamic field
Introduction of Computer Science   Computer Science research forms the backbone of the digital age, driving innovation and shaping the future of technology. This dynamic field explores the design, development,
Introduction of Decision Sciences   Decision Sciences research serves as a compass for informed decision-making across various industries and domains. This multidisciplinary field combines elements of mathematics, economics, psychology, and

Biochemistry

Introduction of Biochemistry

Biochemistry is a captivating scientific discipline that delves into the intricate world of molecules and processes within living organisms. It serves as the bridge between biology and chemistry, unraveling the molecular mechanisms that underlie life, health, and disease. Biochemists explore the structure, function, and interactions of biological molecules, shedding light on fundamental processes from cellular energy production to genetic expression.

Enzyme Kinetics:

Understanding the kinetics of enzymes, the catalysts of biological reactions, is a core aspect of biochemistry. Researchers investigate how enzymes facilitate reactions, regulate metabolic pathways, and impact overall cellular function.

Metabolic Pathways:

Biochemists study the complex networks of metabolic pathways that control the conversion of nutrients into energy and essential molecules. This subfield is vital for understanding health, disease, and drug development.

Protein Folding and Structure:

The three-dimensional structure of proteins and the process of protein folding are central to biochemistry. Researchers explore how misfolded proteins can lead to diseases such as Alzheimer’s and Parkinson’s.

Genomics and DNA:

Biochemists investigate the structure and function of DNA, unraveling the code of life. They explore DNA replication, repair, and how genes are regulated, contributing to advances in genetics and biotechnology.

Drug Discovery and Biochemical Engineering:

Biochemical research plays a pivotal role in drug discovery, designing medications that target specific biochemical pathways. Biochemical engineering involves the optimization of biological processes for the production of biofuels, pharmaceuticals, and other products.

Introduction of Agricultural and Biological Sciences Agricultural and Biological Sciences research plays a pivotal role in addressing the multifaceted challenges of our ever-evolving world. This field encompasses a wide array
Introduction of Arts and Humanities Arts and Humanities research represents the intellectual and creative exploration of the human experience, culture, and society. This broad field encompasses a rich tapestry of
Introduction of Biochemistry Biochemistry is a captivating scientific discipline that delves into the intricate world of molecules and processes within living organisms. It serves as the bridge between biology and
Introduction of Genetics and Molecular Biology Genetics and Molecular Biology are at the forefront of understanding the intricate machinery that governs life itself. This dynamic field investigates the genetic material
Introduction of Business Business research is the driving force behind informed decision-making in the corporate world. It encompasses an array of methodologies and disciplines that aim to understand and improve
Introduction of Management and Accounting Management and Accounting research is the backbone of effective decision-making in organizations, spanning from the corporate world to the public sector. It encompasses the systematic
Introduction of Chemical Engineering   Chemical Engineering research plays a pivotal role in transforming raw materials into valuable products, advancing environmental sustainability, and developing innovative solutions across various industries. It
Introduction of Chemistry    Chemistry research lies at the heart of our understanding of matter and its interactions, and it's a cornerstone of scientific progress. Researchers in this dynamic field
Introduction of Computer Science   Computer Science research forms the backbone of the digital age, driving innovation and shaping the future of technology. This dynamic field explores the design, development,
Introduction of Decision Sciences   Decision Sciences research serves as a compass for informed decision-making across various industries and domains. This multidisciplinary field combines elements of mathematics, economics, psychology, and