Dr. Rodolfo Pinto Almazán | Neuropharmacology | Best Researcher Award

Dr. Rodolfo Pinto Almazán, Escuela Superior de Medicina, IPN, Mexico

Dr. Rodolfo Pinto Almazán is a prominent researcher and professor specializing in biomedical sciences and pharmacology. Currently a Level II member of the National System of Researchers (SNI) and a professor at the Instituto Politécnico Nacional (IPN), Mexico, he has made significant contributions to metabolic and neurodegenerative disease research. With a postdoctoral fellowship at USC and Children’s Hospital Los Angeles, Dr. Pinto has authored groundbreaking studies on oxidative stress and brain function. His honors include the Best Research Manuscript Award (2023) and multiple accolades for his impactful research. 📚🔬👨‍🔬🎓

Publication Profile

Scopus

Research Experience and Achievements

Dr. Rodolfo Pinto Almazán is a distinguished researcher with extensive experience in biomedical sciences. He has been a member of the National System of Researchers (SNI) since 2016, currently at Level II. Dr. Pinto is a professor at the Instituto Politécnico Nacional (IPN) and has worked in various prestigious roles, including postdoctoral research at the University of Southern California (USC) and Children’s Hospital Los Angeles. He has contributed significantly to the study of metabolic and neurodegenerative diseases. His career includes multiple research fellowships and awards. 📚🔬🎓👨‍🔬

Educational Background

Dr. Rodolfo Pinto Almazán holds a distinguished academic background in biomedical sciences. He completed his postdoctoral fellowship at the Keck School of Medicine, USC, and Children’s Hospital Los Angeles (2016–2017), studying sex differences in the central nervous system due to early-life stress. He earned his Ph.D. in Biomedical Sciences from the National Autonomous University of Mexico (UNAM) in 2014, focusing on oxidative stress in the hippocampus. Dr. Pinto also holds a Master’s degree in Pharmacology from the Instituto Politécnico Nacional (IPN), where he studied tau protein activation. His Bachelor’s degree in Pharmaceutical Chemistry was awarded by La Salle University, Mexico. 🎓🔬📚👨‍🔬

Technical Experience

Dr. Rodolfo Pinto Almazán possesses extensive technical expertise in histological and molecular techniques. He is skilled in cryosectioning, immunohistochemistry, and cellular staining. His molecular techniques include DNA/RNA extraction, PCR, ELISA, and Western Blot. Dr. Pinto is proficient with laboratory equipment such as HPLC, NanoDrop, cryostats, thermal cyclers, histoquinescence, and both confocal and optical microscopes. He has hands-on experience with animal handling, including injections, surgeries, ovariectomies, and behavioral tests like the Plus Maze and Morris Water Maze. He also excels in laboratory management, overseeing training, budgeting, and protocol optimization. 🧪🔬🧑‍🔬🐁💻

Teaching Experience

Dr. Rodolfo Pinto Almazán has extensive teaching experience across various levels. He served as an invited professor for the “Molecular Bases of Neurological Diseases” course in the Doctoral program in Biomedical Sciences at UNAM in 2017. He has also taught multiple courses in the Master’s program in Health Sciences at the Escuela Superior de Medicina (ESM, IPN) including Clinical Research, Bioethics, and Biostatistics. In addition, Dr. Pinto has taught Medical Residency courses in Pharmacology, Biochemistry, and Research Methodology at institutions like HRAEI, UAEH, and IMSS. His undergraduate teaching spans subjects like Biochemistry, Cellular Biology, and Pharmacology at UVM, demonstrating his wide-ranging expertise in medical and health sciences education. 📚🧑‍🏫💉

Research Focus

Dr. Rodolfo Pinto Almazán’s research focuses primarily on medical mycology, neuroprotection, and metabolic health. His work explores the neuroprotective effects of sex steroids in spinal cord injury, the virulence factors of fungi like Microsporum canis and Nakaseomyces glabratus, and their association with various skin diseases. Additionally, his research includes investigating metabolic disorders, inflammation, and the effects of omega-3 fatty acids in COVID-19 patients. His contributions span topics such as trauma, fungal infections, and neurodegenerative conditions, emphasizing the importance of therapeutic interventions. 🔬🧠🦠🧑‍🔬

Publication Top Notes

Effect of Chronic Tibolone Administration on Memory and Choline Acetyltransferase and Tryptophan Hydroxylase Content in Aging Mice – Castillo-Mendieta, T., Bautista-Poblet, G., Coyoy-Salgado, A., Neri-Gómez, T., Guerra-Araiza, C. (2024) 🧠📚 – 0 citations
Mortality-Associated Factors in a Traumatic Brain Injury Population in Mexico – Martínez-Herrera, E., Galindo-Oseguera, E., Castillo-Cruz, J., Arellano-Ramírez, A., Pinto-Almazán, R. (2024) ⚠️💀 – 0 citations
Evaluating Sex Steroid Hormone Neuroprotection in Spinal Cord Injury in Animal Models: Is It Promising in the Clinic? – Coyoy-Salgado, A., Segura-Uribe, J., Salgado-Ceballos, H., Moralí de la Brena, G., Guerra-Araiza, C. (2024) 🧠💉 – 0 citations
Cutaneous Fusarium Disease and Leukaemias: A Systematic Review – Cortés-López, P.N., Guzmán-Montijo, E., Fuentes-Venado, C.E., Pinto-Almazán, R., Martínez-Herrera, E. (2024) 🦠🩺 – 0 citations
Fungal Melanonychia: A Systematic Review – Rodríguez-Cerdeira, C., Martínez-Herrera, E., Cortés-López, P.N., Vega-Sánchez, D.C., Pinto-Almazán, R. (2024) 🦠💅 – 2 citations
Remarkable Phenotypic Virulence Factors of Microsporum canis and Their Associated Genes: A Systematic Review – Vite-Garín, T., Estrada-Cruz, N.A., Hernández-Castro, R., Martínez-Herrera, E., Pinto-Almazán, R. (2024) 🦠💪 – 4 citations
Virulence and Resistance Factors of Nakaseomyces glabratus (formerly known as Candida glabrata) in Europe: A Systematic Review – Rodríguez-Cerdeira, C., Pinto-Almazán, R., Saunte, D.M.L., Prohic, A., Martínez-Herrera, E. (2024) 🦠🔬 – 1 citation
Effectiveness of Omega-3 Fatty Acid Supplementation in Improving the Metabolic and Inflammatory Profiles of Mexican Adults Hospitalized with COVID-19 – Rodríguez-Vera, D., Salazar, J.R., Soriano-Ursúa, M.A., Loza-Mejía, M.A., Pinto-Almazán, R. (2024) 🐟💪 – 1 citation
In Silico and In Vivo Evaluation of the Maqui Berry (Aristotelia chilensis (Mol.) Stuntz) on Biochemical Parameters and Oxidative Stress Markers in a Metabolic Syndrome Model – Castillo-García, E.L., Cossio-Ramírez, A.L., Córdoba-Méndez, Ó.A., Gallardo, J.M., Guerra-Araiza, C. (2023) 🍇⚖️ – 0 citations
Main Phenotypic Virulence Factors Identified in Trichophyton Rubrum – Martínez-Herrera, E., Moreno-Coutiño, G., Fuentes-Venado, C.E., Pinto-Almazán, R., Rodríguez-Cerdeira, C. (2023) 🦠🦶 – 3 citations

Dr. Linjing Mu | Brain PET Imaging Award | Best Researcher Award

Dr. Linjing Mu, ETH Zurich, Switzerland

🔬 Dr. Linjing Mu pursued doctoral research at Nankai University, followed by a post-doctoral fellowship at Basel University, Switzerland. With expertise in radiopharmaceutical sciences, Dr. Mu led research teams at University Hospital Zurich and ETH Zurich, focusing on lead structure discovery, ligand synthesis, and radiolabeling method development. A prolific author, Dr. Mu has 106 peer-reviewed publications, including 10 as last and corresponding author, and 19 as the first author. Co-investigator on 10 patents, Dr. Mu has presented internationally and collaborated with industry leaders like Bayer Schering, Novartis, and Roche, contributing significantly to drug discovery and clinical translations.

Publication Profile:

Scopus

Orcid

Education:

Doctoral Research in Chemistry Department, Nankai University (1993-1996)

Post-Doctoral Fellow, Basel University, Switzerland (1996-2001)

Experience:

Team Leader in the field of Radiopharmaceutical Sciences, Group of Prof. Schubiger (2001-2010)

Head of Research, Radiopharmacy, University Hospital Zurich (2010-2021)

Senior Scientist, Prof. Schibli’s Group, ETH Zurich (2021-Present)

Research Expertise:

Lead Structure Finding based on Literature and Patents

Design and Synthesis of Novel Ligands

Structure-Activity Relationship Studies

Radiolabeling Method Development

In Vitro and In Vivo Evaluation

Academic Achievements:

Co-authored 106 Peer-Reviewed Publications

Last and Corresponding Author on 10, First Author on 19 (H-Factor 29, Scopus)

Co-Investigator on 10 Patent Applications

Contributed to International Conferences as Invited Speaker, Oral and Poster Presenter

Research Focus:

🔬 Dr. Linjing Mu’s research focus lies at the intersection of neuroimaging and drug development, particularly in the field of molecular imaging for neurodegenerative diseases like Alzheimer’s. Their work encompasses the development and optimization of radioligands targeting specific molecular pathways implicated in neurodegeneration. Through PET/MRI studies and the exploration of novel PET tracers, such as (R)-[18F]YH134 and (R)-[18F]PSS232, Dr. Mu aims to deepen our understanding of disease mechanisms and identify potential therapeutic targets. This research not only sheds light on disease pathology but also paves the way for the development of new diagnostic tools and pharmacological interventions.

Publication Top Notes:

📄 Wang, J. et al. Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer’s disease: A [18F]PSS232 PET/MRI study. Published in Alzheimer’s Research and Therapy, 2024. Cited by: 0.

📄 He, Y. et al. Identification of (R)-[18F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development. Published in Journal of Nuclear Medicine, 2024. Cited by: 0.

📄 Boccalini, C. et al. The impact of tau deposition and hypometabolism on cognitive impairment and longitudinal cognitive decline. Published in Alzheimer’s and Dementia, 2024. Cited by: 1.

📄 Trachsel, B. et al. Reducing kidney uptake of radiolabelled exendin-4 using variants of the renally cleavable linker MVK. Published in EJNMMI Radiopharmacy and Chemistry, 2023. Cited by: 0.

📄 Lu, Y. et al. Proof-of-concept optimization of a copper-mediated 18F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation. Published in Lab on a Chip, 2023. Cited by: 1.

📄 Ni, R. et al. Imaging increased metabolism in the spinal cord in mice after middle cerebral artery occlusion. Published in Photoacoustics, 2023. Cited by: 0.

📄 Zechner, M. et al. In Vitro and In Vivo Evaluation of ABCG2 (BCRP) Inhibitors Derived from Ko143. Published in Journal of Medicinal Chemistry, 2023. Cited by: 1.

📄 Bengs, S. et al. Rest/stress myocardial perfusion imaging by positron emission tomography with 18F-Flurpiridaz: A feasibility study in mice. Published in Journal of Nuclear Cardiology, 2023. Cited by: 3.

📄 Peretti, D.E. et al. ATN profile classification across two independent prospective cohorts. Published in Frontiers in Medicine, 2023. Cited by: 0.

📄 He, Y. et al. Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain. Published in European Journal of Medicinal Chemistry, 2022. Cited by: 2.

Rodolfo Pinto Almazán | Neuropharmacology | Best Researcher Award