Sharada Mokkapati | Cancer Biology | Best Researcher Award

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Dr. Sharada Mokkapati | Cancer Biology | Best Researcher Award

Dr. Sharada Mokkapati, The UT MD Anderson Cancer Center, United States

Dr. Sharada Mokkapati is an Assistant Professor of Urology (Research) at UT MD Anderson Cancer Center, specializing in oncology, molecular biology, and gene therapy. With a PhD in Genetics from the University of Cologne, Germany (2007), Dr. Mokkapati has contributed significantly to bladder cancer research. She was a key team member in the first FDA-approved gene therapy for bladder cancer and has extensive experience with gene therapy vector development, RNA/DNA molecular techniques, and NextGen sequencing. Her research also includes the identification of miRNA biomarkers and the study of tumor metabolism in gene therapy responses. Dr. Mokkapati has received multiple awards, including the Dodie P. Hawn Fellowship and the Lennox K. Black International prize for excellence in medicine. She is also an adhoc reviewer for journals like BMC Cancer and has co-authored numerous influential publications on bladder cancer and cancer therapy.

Publication Profile

Scopus

Education

Dr. Sharada Mokkapati earned her PhD in Genetics from the University of Cologne, Germany, in February 2007. Her academic journey has focused on genetic research, exploring complex biological systems to understand various genetic disorders. With a robust foundation in genetic principles, she has contributed significantly to the scientific community through research, publications, and collaborations. Dr. Mokkapati’s work has emphasized advancing knowledge in molecular genetics, genetic markers, and hereditary diseases, making a lasting impact on the field. Her dedication continues to inspire the next generation of genetic researchers. πŸŒ±πŸ“š

 

Professional Experience 🌟

Dr. Sharada Mokkapati has an extensive career in academia and research. Since 2020, she has served as an Assistant Professor in Urology (Research) at the UT MD Anderson Cancer Center. Previously, she was an Instructor in Urology (Research) at the same institution from 2015 to 2020. Dr. Mokkapati’s academic journey began with a postdoctoral fellowship in the Department of Genetics at UT MD Anderson Cancer Center (2008-2015). Her early career includes graduate studies in Dermatology at the University of Cologne (2002-2007), and research roles at SPIC Science Foundation and Malladi Drugs & Pharmaceuticals in India. πŸ§¬πŸ”¬

 

 

Research Achievements πŸ§¬πŸ”¬

Dr. Sharada Mokkapati has made significant contributions to the field of oncology and gene therapy. She was a key team member in the development of the first FDA-approved gene therapy for bladder cancer. With extensive experience in oncology, molecular biology, biochemistry, biotechnology, and biomedical research, Dr. Mokkapati has developed and validated vectors for gene therapy. She is highly proficient in RNA, DNA, protein molecular techniques, biochemical assays, and NextGen sequencing. Additionally, Dr. Mokkapati excels in using both xenograft and genetically engineered mouse models for translational biology studies and managing research-related compliance and clinical trial databases. πŸ§ͺπŸ’‘

 

Awards and Honors πŸ…πŸŽ“

Dr. Sharada Mokkapati has been recognized with several prestigious awards throughout her career. She was honored with the “Dodie P. Hawn Fellowship in Genetics” at UT MD Anderson Cancer Center. Dr. Mokkapati also received the “Travel Award-Lennox K. Black International Prize for Excellence in Medicine” for her contribution to the 12th International Symposium on Basement Membranes in Philadelphia. As a team member, she contributed to the technology transfer for amylase and tannase at SPIC Science Foundation, India. Additionally, she qualified the “National Eligibility Test for Lectureship (NET)” and received the “Dr. T. Ramachandra Rao Memorial Gold Medal” for academic excellence in her Master’s studies. πŸ†πŸ§¬

 

 

Research Focus πŸ”¬πŸ’‘

Dr. Sharada Mokkapati’s research primarily focuses on oncology, molecular biology, and gene therapy in the context of bladder cancer. She has contributed extensively to the molecular profiling of bladder cancer, identifying relevant subtypes for biomarker discovery. Her work also includes the development and validation of gene therapy vectors, particularly in non-muscle invasive bladder cancer. Dr. Mokkapati is proficient in RNA/DNA/protein molecular techniques, biochemical analysis, and NextGen sequencing, using mouse models to address both basic biological and translational studies. Her efforts aim to integrate gene therapies into bladder cancer treatment paradigms. 🧬🧫🎯

 

Publication Top Notes

  • Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery (2025) – Cited by 0 πŸ”¬πŸ“š
  • Integrating gene therapy into the treatment paradigm for non-muscle invasive bladder cancer (2025) – Cited by 0 πŸ§¬πŸ’‘
  • Concomitant antihistamine administration improves survival outcomes in urothelial carcinoma treated with atezolizumab (2025) – Cited by 0 πŸ’ŠπŸ“ˆ
  • Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon Ξ± gene therapy in a murine bladder cancer model (2024) – Cited by 0 πŸ§ͺ🧬
  • Interferon gene therapy with nadofaragene firadenovec for bladder cancer: from bench to approval (2023) – Cited by 7 πŸ₯πŸ”¬
  • The current status of gene therapy in bladder cancer (2023) – Cited by 8 πŸ“–πŸ”
  • Lentiviral interferon: A novel method for gene therapy in bladder cancer (2022) – Cited by 8 🧬πŸ§ͺ
  • Antiadenovirus Antibodies Predict Response Durability to Nadofaragene Firadenovec Therapy in BCG-unresponsive Non-muscle-invasive Bladder Cancer (2022) – Cited by 16 πŸ§ͺπŸ”¬
  • TCF21 promotes luminal-like differentiation and suppresses metastasis in bladder cancer (2020) – Cited by 7 🧬πŸ’₯
  • Generation of a novel mouse strain with conditional, cell-type specific, expression of DND1 (2019) – Cited by 2 πŸπŸ”¬

 

 

 

Hyunsook Lee | Cancer Cell Biology | Best Researcher Award

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Prof Dr. Hyunsook Lee | Cancer Cell Biology | Best Researcher Award

Prof Dr. Hyunsook Lee, Seoul National University/College of Natural Sciences/Dept. of Biological Sciences, South Korea

πŸŽ“ Prof. Dr. Hyunsook Lee is an accomplished scientist with a diverse educational background: B.Sc. from Ewha Womans University, M.Sc. from Seoul National University, and a Ph.D. from the University of Cambridge under Prof. Ashok Venkitaraman. Her research focused on cell cycle checkpoints and the breast cancer susceptibility gene, Brca2. Dr. Lee holds key positions including Head of AI-Bio Research Center and Dean for Research Affairs at Seoul National University. She co-founded Next & Bio, later acquired by Kolmar Holdings, and has served on advisory boards for STEPI and the Ministry of Education in Korea. 🧬

 

Publication profile

Google Scholar

πŸŽ“ Education

Prof. Dr. Hyunsook Lee earned her B.Sc. from Ewha Womans University (1986-1990) and M.Sc. from Seoul National University (1990-1992). She completed her Ph.D. at the University of Cambridge (1996-1999), focusing on cell cycle checkpoints and the breast cancer gene, Brca2, under the supervision of Prof. Ashok Venkitaraman.

🌟 Professional Achievements

Dr. Lee holds numerous prestigious positions, including Head of AI-Bio Research Center (since 2023) and co-founder of Next & Bio (acquired by Kolmar Holdings in 2022). She served as Dean for Research Affairs at Seoul National University and on advisory committees for STEPI and the Ministry of Education in Korea.

Experience

Her career includes roles as a Visiting Scientist at Harvard Medical School and the University of Washington, and she contributed significantly to institutions like Samsung Advanced Institute of Technology.

 

Research Focus

Dr. H. Lee’s research spans across several fields, primarily focusing on technological advancements and their impacts. His work includes studies on augmented and virtual reality, high-frequency electrical models, and the application of IT in organizational contexts. With interests ranging from cultural heritage tourism to smart home services, Dr. Lee’s research integrates diverse disciplines to explore innovative solutions and their societal implications. 🌐

Publication Top Notes

πŸ“„ Nature 425 (6961), 968-973 – Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes (2152 citations, 2003)

πŸ“Š Public administration review 66 (3), 370-385 – The impact of organizational context and information technology on employee knowledge-sharing capabilities (1149 citations, 2006)

πŸ”¬ Molecular cell 1 (3), 347-357 – Involvement of Brca2 in DNA repair (789 citations, 1998)

πŸ–₯️ IEEE Journal of Solid-state circuits 19 (6), 820-827 – Full-speed testing of A/D converters (702 citations, 1984)

πŸ›οΈ Information and communication technologies in tourism 2016 – Effects of virtual reality and augmented reality on visitor experiences in museums (636 citations, 2016)

🧲 Physical Review Bβ€”Condensed Matter and Materials Physics 72 (17), 174431 – Magnetic ordering at the edges of graphitic fragments (563 citations, 2005)

🧠 Brain research 971 (2), 197-209 – Astrocytes accumulate AΞ²42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains (538 citations, 2003)

πŸ”Œ IEEE Transactions on Components, Packaging and Manufacturing Technology 1 (2) – High-frequency scalable electrical model and analysis of a through silicon via (TSV) (509 citations, 2011)

πŸ—οΈ Cement and Concrete research 32 (8), 1313-1318 – Evaluation of the bond properties between concrete and reinforcement as a function of the degree of reinforcement corrosion (496 citations, 2002)

πŸ›οΈ Journal of Travel Research 57 (5), 627-643 – The role of augmented reality for experience-influenced environments: The case of cultural heritage tourism in Korea (403 citations, 2018)

🏠 Industrial Management & Data Systems 117 (1), 68-89 – User acceptance of smart home services: an extension of the theory of planned behavior (395 citations, 2017)

🌿 Proceedings of the National Academy of Sciences 87 (19), 7633-7637 – Wound-induced accumulation of mRNA containing a hevein sequence in laticifers of rubber tree (362 citations,