Chryslaine Rodríguez-Tanty | Chemistry Award | Best Researcher Award

Mrs. Chryslaine Rodríguez-Tanty | Chemistry Award | Best Researcher Award

Mrs. Chryslaine Rodríguez-Tanty, Centro de Neurociencias de Cuba, Cuba

Mrs. Chryslaine Rodríguez-Tanty is a prominent researcher focused on Alzheimer’s disease and neurodegeneration. She is known for her work on Amylovis-201, a dual-target ligand that acts as an anti-amyloidogenic compound and a potent σ1 receptor agonist. Her research demonstrates Amylovis-201’s effectiveness in inhibiting Aβ peptide aggregation and its neuroprotective effects through σ1 receptor activation. Chryslaine’s contributions are pivotal in developing innovative therapies for neurodegenerative diseases. 🧠💊🔬

Publication profile

Scopus

Google Scholar

Research Focus

Chryslaine Rodríguez-Tanty is primarily focused on the development of therapeutic agents targeting neurodegenerative diseases and other conformational disorders. Her work includes the study of amyloid structures, drug discovery for Alzheimer’s disease, and the development of chemical chaperones. She has also contributed to research on polymorphic amyloid structures in diabetes and the synthesis of peptide-oligonucleotide hybrids. Chryslaine’s research spans organic chemistry, biochemistry, and pharmacology, aiming to create innovative treatments for complex diseases. 🧬🧠💊🔬

Publication Top Notes

  • Drug development in conformational diseases: A novel family of chemical chaperones that bind and stabilise several polymorphic amyloid structures – PLoS One 10 (9), e0135292, 2015 (Cited by: 30) 🧬💊
  • Diabetes Drug Discovery: hIAPP1–37 Polymorphic Amyloid Structures as Novel Therapeutic Targets – Molecules 23 (3), 686, 2018 (Cited by: 27) 🩺🍬
  • [18F] Amylovis as a Potential PET Probe for β-Amyloid Plaque: Synthesis, in Silico, in vitro and in vivo Evaluations – Current Radiopharmaceuticals 12 (1), 58-71, 2019 (Cited by: 17) 🧠🔬
  • Alternative Procedures for the Synthesis of Methionine‐Containing Peptide− Oligonucleotide Hybrids – European Journal of Organic Chemistry 2000 (13), 2495-2500, 2000 (Cited by: 16) 🧬🧪
  • A new naphthalene derivative with anti-amyloidogenic activity as potential therapeutic agent for Alzheimer’s disease – Bioorganic & Medicinal Chemistry 28 (20), 115700, 2020 (Cited by: 14) 🧠💊
  • Use of a chimeric synthetic peptide from the core p19 protein and the envelope gp46 glycoprotein in the immunodiagnosis of HTLV-II virus infection – Preparative Biochemistry and Biotechnology 33 (1), 29-38, 2003 (Cited by: 10) 🦠🧬
  • Introduction of an immunochemical label in a cytidine analogue – Nucleosides, Nucleotides & Nucleic Acids 14 (1-2), 219-228, 1995 (Cited by: 10) 🧪🔬
  • 2′, 3′-Didehydro-3′-deoxythymidine N-methyl-2-pyrrolidone solvate (D4T· NMPO) – Acta Crystallographica Section C: Crystal Structure Communications 56 (5), 2000 (Cited by: 9) 🔬🧬
  • Synthesis of 5-Methyl-2′-O-Deoxycytidine Analogs to Determine Monoclonal Antibody Specificity in the Recognition of the 6-(p-Bromobenzoylamino) Caproyl – Nucleosides & Nucleotides 16 (4), 455-467, 1997 (Cited by: 8) 🧪🔬
  • Identificación y caracterización in silico de la zona de interacción entre el péptido beta-amiloide y compuestos derivados del naftaleno – Revista CENIC. Ciencias Químicas 43, 2012 (Cited by: 7) 🧠🔍

kamal Al jorani | Chemistry | Industry Impact Academic Award

kamal Al jorani | Chemistry | Industry Impact Academic Award

Assist Prof Dr kamal Al jorani,Wasit University,Iraq

Assist. Prof. Dr. Kamal Rashid Al-Jorani is a renowned chemist specializing in organic, inorganic, and medicinal chemistry 🌟. He earned his PhD in Chemistry from the University of Mustansiriyah in 2019, focusing on benzimidazole derivatives. Dr. Al-Jorani is currently an Assistant Professor and Laboratory Head at the university’s Chemistry Department 🧪. His expertise includes heterocyclic compound synthesis, drug synthesis, and coordination chemistry 🔬. He has authored several notable publications, including works on novel heterocyclic compounds and their pharmacological properties 📚. Dr. Al-Jorani’s research contributions have significant implications in both academic and pharmaceutical fields 🌍.

Publication profile

Orcid

Education

Kamal Rashid Al-Jorani’s academic journey spans through prestigious institutions, primarily the University of Mustansiriyah. He attained his Doctor of Philosophy in Chemistry in 2019, focusing on the synthesis, characterization, and preliminary pharmacological study of Benzimidazole Derivatives. Prior to his doctoral degree, Al-Jorani earned a Master’s in Chemistry in 2010, delving into the stability and stability constant of complexes formation between imidazole derivatives and various metal ions through potentiometric methods. His foundational academic achievement includes a Bachelor’s in Chemistry from the University of Mustansiriyah in 2008.

 

Teaching

Kamal Rashid Al-Jorani holds the esteemed position of Assistant Professor, reflecting his dedication to academia and his expertise in the field of chemistry. Currently, he serves as a pivotal figure in the Chemistry Department, where he undertakes the role of Teaching and Lab Head. His responsibilities extend to overseeing the instruction and practical application of Organic Chemistry concepts to third-year students. Moreover, he assumes leadership as the Lab Head for the Laboratory of Organic Chemistry, further enriching the educational experience for aspiring chemists within the department. Through his roles, Al-Jorani contributes significantly to the development and enhancement of academic programs and laboratory practices.

Research focus

Kamal Rashid Al-Jorani is a researcher whose focus lies in medicinal and pharmaceutical chemistry. His work primarily centers on the synthesis and characterization of heterocyclic compounds, particularly those involving benzimidazole and imidazole derivatives. These compounds are often explored for their pharmacological potential and applications in areas such as drug synthesis and antibacterial activity. Additionally, he delves into coordination chemistry to study metal complexes, which has implications for solar cell technology and other material sciences applications. His diverse expertise bridges organic chemistry and inorganic chemistry, addressing both biological and material challenges. 🌿🔬💊🌟

Publication top notes

 10.1016/j.kjs.2024.100271

Synthesis, Characterization, and Implementations for Dye Solar Cell of New Hematite Nanoparticles Using Tetrasubstituted Imidazole Containing a Benzimidazole Moiety

Synthesis, Characterization, and Implementations for Dye Solar Cell of New Hematite Nanoparticles Using Tetrasubstituted Imidazole Containing a Benzimidazole Moiety

 10.1007/s11224-022-02069-w

Synthesis, Structure Elucidation, and Pharmacological Study of New Hydrazinylidene Derivatives Using Benzimidazole as a Scaffold

Synthesis and characterization of a novel benzimidazole derivative: Solvatochromic and acid-base indicator applications