Dr. Zhang Hu, Yangzhou University, China
Dr. Zhang Hu, PhD, is a tutor at Yangzhou University, China. He holds a doctorate from Southeast University (2023) and was recruited under the ‘Young Hundred’ program. His research focuses on the carcinogenic effects of environmental pollutants, particularly N-nitrosamines and their link to esophageal cancer (EC). Dr. Zhang has published over 20 SCI papers in top journals like Environment International and Environmental Pollution. He has led research projects funded by China’s National Natural Science Foundation and Postdoctoral Foundation. Dr. Zhang is a member of the Jiangsu Society of Environmental Mutagens. 🌍🧬
Publication Profile
Orcid
Academic and Professional Background 🎓🌍
Dr. Zhang Hu, PhD, is a Master’s Degree Supervisor at Yangzhou University, China, recruited under the prestigious ‘Young Hundred’ program. He earned his doctorate from Southeast University in 2023 and was selected for the ‘Green Yang Jinfeng Doctor’ program. His primary research focus lies in the carcinogenic effects of environmental pollutants and their mechanisms. Dr. Zhang has published over 20 SCI papers in prominent environmental toxicology journals such as Environment International and Environmental Pollution. He has led projects funded by the National Natural Science Youth Foundation of China and the China Postdoctoral Foundation, and contributed to projects under the National Natural Science Foundation of China. 🧬📚
Research and Innovations
Dr. Zhang Hu’s research focuses on the carcinogenicity of N-nitrosamines, which form during nitrite solidification in diets and chlorination by-products in drinking water. These compounds have raised significant concerns due to their toxicological effects, particularly in the development of esophageal cancer (EC). Humans are often exposed to multiple nitrosamines, increasing the risk of EC. Dr. Zhang’s studies have highlighted the crucial role of lipid metabolism disorders in the progression of EC induced by nitrosamines. While much research has been conducted, the link between nitrosamine exposure and lipid metabolism disorders in EC remains underexplored. 🧬🍽️
Areas of Research
Dr. Zhang Hu’s primary areas of research focus on the intersection of environment and health, with a particular emphasis on the mechanisms behind direct carcinogens. His work investigates how environmental pollutants, such as N-nitrosamines, contribute to the development of various cancers, especially esophageal cancer. By exploring the toxicological effects of these carcinogens, Dr. Zhang aims to understand their biological impact on human health. His research not only sheds light on the pathways through which environmental factors influence cancer but also seeks to identify potential biomarkers and therapeutic targets for prevention and treatment. 🌱💡
Publication Top Notes
- The association between N-nitrosamines exposure and lipid metabolism in the high incidence area of esophageal cancer: A case-control analysis – Environmental Pollution (2024) 🌿 | DOI: 10.1016/j.envpol.2024.125271 | Cited by: 20+ 📚
- Multi-omics analysis revealed NMBA induced esophageal carcinoma tumorigenesis via regulating PPARα signaling pathway – Environmental Pollution (2023) 🧬 | DOI: 10.1016/j.envpol.2023.121369 | Cited by: 15+ 🔬
- LncRNA RPL34-AS1 suppresses the proliferation, migration and invasion of esophageal squamous cell carcinoma via targeting miR-575/ACAA2 axis – BMC Cancer (2022) 🧬 | DOI: 10.1186/s12885-022-10104-6 | Cited by: 12+ 📚
- Lipid metabolism disorders contribute to hepatotoxicity of ICR mice induced by nitrosamines exposure – Environment International (2022) 🌍 | DOI: 10.1016/j.envint.2022.107423 | Cited by: 10+ 🧪
- The dysregulation of unsaturated fatty acid-based metabolomics in the MNNG-induced malignant transformation of Het-1A cells – Environmental Science and Pollution Research (2022) ⚗️ | DOI: 10.1007/s11356-021-17622-z | Cited by: 8+ 🧬
- Dysregulation of fatty acid metabolism associated with esophageal inflammation of ICR mice induced by nitrosamines exposure – Environmental Pollution (2021) 🌱 | DOI: 10.1016/j.envpol.2021.118680 | Cited by: 5+ 🏥