Ismael Lares-Asseff | Pharmacology | Lifetime achievement Award

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Assoc. Prof. Dr. Ismael Lares-Asseff | Pharmacology | Lifetime achievement Award

Assoc. Prof. Dr. Ismael Lares-Asseff, Instituto Politécnico Nacional, CIIDIR Durango, Mexico

Dr. Ismael Lares-Asseff, a prominent Mexican researcher, holds a degree in Medicine from UJED and a specialty in Pediatrics from IMAN and UNAM. He earned his Master’s and Ph.D. in Medical Sciences from UNAM, receiving the prestigious “Gabino Barreda Medal.” Mentored by renowned researcher Dr. Joaquín Cravioto, Dr. Lares founded Latin America’s first Clinical Pharmacokinetics Laboratory in 1982. His work spans pediatric pharmacokinetics, malnutrition, and pharmacogenetics among diverse ethnic groups, and he authored influential books like Clinical Pharmacology in Pediatrics and Pharmacogenomics in Latin America. With 190 publications, 671 citations, and numerous awards, he is a leader in personalized medicine.

 

Publication Profile

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Background and Academic Achievements

Assoc. Prof. Dr. Ismael Lares-Asseff holds a distinguished background in medicine, earning degrees and accolades throughout his extensive career. With an MD from the Universidad Juárez del Estado de Durango (UJED), he specialized in Pediatrics through the Children’s Hospital of IMAN and the National Autonomous University of Mexico (UNAM). His academic journey culminated in a Master’s and Doctorate in Medical Sciences from UNAM, where he was awarded the “Gabino Barreda Medal” for his outstanding academic achievements.

Contributions to Pediatric Research and Clinical Pharmacokinetics

Under the mentorship of Dr. Joaquín Cravitoto, a globally respected figure in pediatric research, Dr. Lares-Asseff developed Mexico’s first Clinical Pharmacokinetics Laboratory in 1982. His early research primarily focused on understanding the impact of malnutrition on pediatric pharmacokinetics, producing findings published in prestigious journals. These works led to his internationally recognized book, Clinical Pharmacology in Pediatrics: Pharmacokinetics and Pharmacogenomics, awarded by the Mexican Academy of Pediatrics.

Conclusion

Assoc. Prof. Dr. Ismael Lares-Asseff is an ideal candidate for the Research for Lifetime Achievement Award. His contributions to pediatric pharmacology, pharmacogenetics, and personalized medicine embody a lifelong commitment to advancing medical science and patient care.

 

Publication Top Notes

  • 🧬 Influence of Age, Gender, and BMI on IV Pharmacokinetics of Buprenorphine in Children Undergoing Orthopedic Surgery, Rivera-Espinosa, L., Vicencio-Rosas, E., et al., Dose-Response, 2024, 0 citations.
  • 👨‍⚕️ Population Pharmacokinetics and Pharmacodynamics of L-asparaginase and Its Impact on Pancreatitis in Leukemia Patients, Gándara-Mireles, J.A., Lares-Asseff, I., et al., Drug and Chemical Toxicology, 2024, 0 citations.
  • 💉 Nutritional Status as a Risk Factor for Doxorubicin Cardiotoxicity in Mexican Children with ALL, Gándara-Mireles, J.A., Lares-Asseff, I., et al., Nutrition and Cancer, 2024, 0 citations.
  • 🧪 Impact of SNPs and Nutrition on Doxorubicin Pharmacokinetics and Cardiotoxicity in Leukemia Patients, Gándara-Mireles, J.A., Lares-Asseff, I., et al., Journal of Oncology Pharmacy Practice, 2023, 3 citations.
  • 🌎 Barriers to Pharmacogenomics in Latin America and the Caribbean: Drug/Gene Pairs, Salas-Hernández, A., Galleguillos, M., et al., Frontiers in Pharmacology, 2023, 9 citations.
  • 📝 Pharmacogenetics and Pharmacogenomics in Latin America: Perspectives, López-Cortés, A., Esperón, P., Lares-Asseff, I., et al., Frontiers in Pharmacology, 2023, 3 citations.
  • 🐾 Silver Nanoparticles in Treating Distemper in Dogs: A Clinical Trial, Gastelum-Leyva, F., Pena-Jasso, A., et al., Viruses, 2022, 2 citations.
  • 🔬 Mitochondrial Dysfunction Caused by Zinc Oxide Nanoparticles, Patrón-Romero, L., et al., Crystals, 2022, 16 citations.
  • 🧬 Effect of Levetiracetam on Placental Transporter Gene Expression in Mice, Blanco-Castañeda, R., et al., Epilepsia, 2022, 0 citations.
  • ❤️ Genetic Polymorphisms and Doxorubicin Cardiotoxicity in Children with ALL, Gándara-Mireles, J.A., Lares-Asseff, I., et al., Pharmacogenetics and Genomics, 2021, 8 citations.

 

 

 

Shubham Sharma | Pharmacology | Best Researcher Award

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Shubham Sharma | Pharmacology | Best Researcher Award

Dr Shubham Sharma, Pfizer, United States

Dr. Shubham Sharma is a leading computational modeler with 8+ years of expertise in theoretical materials science, physics, and chemistry. Holding a Ph.D. in Chemical & Environmental Engineering from Brown University (2021), he specializes in atomistic modeling and solid-form design, notably working at Pfizer where he leads drug de-risking efforts. His research in catalysis, electrochemistry, and crystal structure predictions has earned him over 10 Pfizer Bravo awards. Dr. Sharma’s groundbreaking work is recognized globally, including invited talks at major conferences, advancing both pharmaceutical and renewable energy applications. 💻🔬💊⚡

Publication Profile

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Education

This individual holds a PhD in Chemical & Environmental Engineering from Brown University, USA (2016-2021) 🎓, where they conducted research under the guidance of Andrew A. Peterson 🧑‍🔬. Their academic journey began with a Bachelor of Technology (B. Tech) in Chemical Engineering from the Heritage Institute of Technology, India (2012-2016) 🛠️. With a strong foundation in chemical engineering, they have pursued advanced studies focusing on environmental solutions and sustainability 🌍. Their education showcases a dedication to addressing global environmental challenges through innovative engineering approaches and cutting-edge research 🌱📘.

Work Experience

Currently serving as a Senior Scientist in Computational Materials Science at Pfizer Inc. (July 2022 – present) 🧑‍🔬, this individual leads the Solid Form Design Center (SFDC) focused on de-risking potential drug molecules through advanced statistical and quantum mechanical modeling 💊. They contributed to the success of Zavegepant (Zavzpret™) and Rimegepant (Nurtec™) 🌟. As a core member of the Crystal Structure Prediction team, they specialize in electronic structure theory, density functional theory, and atomistic modeling 🧬. They also collaborate with global industrial and academic partners, lead multiple research proposals, and mentor colleagues in computational science 🔬💻.

Selected conference presentations

Sharma has delivered numerous invited talks and presentations globally 🌍. In 2024, they presented on multi-polymorphic systems at the Crystal Form Consortium Symposium (UK) and computational strategies in pharmaceutical research at UConn (US) and IISER (India) 🧪. Sharma also discussed electrocatalysis at the 8th Global Webinar on Materials Science & Engineering in 2023 🧑‍🏫. Other notable presentations include de-risking medicines at AAPS NERDG (2024) and several studies on oxygen reduction reactions and catalytic properties at AIChE, NECS, ECS, and MRS conferences 🎤. Their work spans computational modeling and applied research in materials science and electrocatalysis ⚛️.

Research Focus

The research focus of Sharma spans electrochemistry, catalysis, and materials science. Sharma investigates the design and stability of catalysts, particularly Pt-based and CoPt alloys, for fuel cells and oxygen reduction reactions (ORR) ⚡️🔋. His work includes dynamic stability, reaction barriers, and potential-controlled reactions, using advanced techniques like density functional theory (DFT) and experimental-theoretical integration. He also explores solid form derisking in pharmaceuticals 💊 and carbon electrodes in redox flow batteries. Sharma’s studies contribute to cleaner energy and advanced catalytic systems 🌍🔬, emphasizing electrochemical stability and performance improvement in energy devices.

 

Publication Top Notes

Hard-magnet L10-CoPt nanoparticles advance fuel cell catalysis

Anisotropic Strain Tuning of L10 Ternary Nanoparticles for Oxygen Reduction

Face-centered tetragonal (FCT) Fe and Co alloys of Pt as catalysts for the oxygen reduction reaction (ORR): A DFT study

Ordered CoPt oxygen reduction catalyst with high performance and durability

Metal dissolution from first principles: Potential-dependent kinetics and charge transfer

Assessment of carbon monoxide exposure in roadside food-vending shanties using coal cookstoves in Kolkata, India

Dynamic stability of Pt-based alloys for fuel-cell catalysts calculated from atomistics

Conclusion

Dr. Shubham Sharma’s innovative research in computational modeling and materials science, alongside his leadership in both academic and industrial collaborations, makes him an exceptional candidate for the Best Researcher Award. His contributions have not only advanced pharmaceutical drug design but also impacted renewable energy research, marking him as a distinguished leader in his field.

Alessandra Bitto | Pharmaceutical Science | Most Cited Paper Award

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Prof Dr. Alessandra Bitto | Pharmaceutical Science | Most Cited Paper Award

Prof Dr. Alessandra Bitto, University of Messina, Italy

👩‍🔬 Prof. Alessandra Bitto, born on August 26, 1979, in Messina, Italy, is a distinguished figure in medical research. Graduating with top honors (110/110 cum laude) in Medicine and Surgery from the University of Messina in 2003, her early career was marked by groundbreaking research on neointimal hyperplasia. Dr. Bitto’s contributions have been recognized globally, earning prestigious awards like the Young Researcher Award and the SIF Award for her work on postmenopausal metabolic syndrome. She has presented her findings at international symposiums, notably in Tokyo, Japan, showcasing her expertise on the effects of genistein aglycone. With a penchant for exploration, Dr. Bitto has enriched her knowledge through educational stints across Europe and the USA, delving into diverse fields from molecular biology to neuroscience. Her dedication to advancing medical science is evident in her role as a Visiting Researcher at renowned institutions like the University of Kentucky. Dr. Alessandra Bitto continues to inspire with her passion for research and her commitment to improving global health.

Publication Profile:

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UNIVERSITY CAREER:

🎓 Dr. Alessandra Bitto, born and raised in Messina, Italy, embarked on her academic journey by pursuing a degree in Medicine and Surgery at the University of Messina. Throughout her university career, she delved into various disciplines, from human anatomy and physiology to pathology and pharmacology. Her dedication to understanding the intricacies of medical science led her to specialize in pharmacology at the Department of Experimental Clinic of Medicine and Pharmacology. Graduating with top honors in July 2003, her research thesis on the role of MAPK ERK and JNK in neointimal hyperplasia garnered widespread acclaim, laying the foundation for her remarkable contributions to the field.

 

AWARDS AND RECOGNITIONS:

🏆 Dr. Alessandra Bitto’s contributions to medical science have been widely recognized through numerous awards and accolades. In 2008, she clinched the prestigious Young Researcher Award from the University of Messina, applauding her outstanding scientific productivity. Her groundbreaking research on the effects of phytoestrogen genistein in postmenopausal metabolic syndrome earned her the SIF Award for the best poster at a national seminar in Pharmacology. Invitations as a keynote speaker at international symposiums further highlighted her expertise, notably in Tokyo, Japan. Her excellence was reaffirmed with the Young Investigator Award for her pioneering work on genistein aglycone’s role in managing secondary osteoporosis, culminating in the SIF-Farmindustria Award in 2009. 🌟

 

EDUCATIONAL EXPERIENCES:

🌍 Dr. Alessandra Bitto’s global academic pursuits have enriched her knowledge and expertise in various fields. From delving into histology at the University of Santiago de Compostela, Spain, to exploring molecular biology in Vienna, Austria, her foreign educational experiences have been diverse and extensive. She further broadened her horizons in infectious diseases at Aarhus University, Denmark, and cardiovascular research at the University of Helsinki, Finland. Her journey continued with immersive experiences in molecular genetics at the University of Barcelona, Spain. Notably, she expanded her insights into neurosciences at the Medical University of South Carolina and cardiovascular research at the University of Kentucky in the USA, solidifying her as a globally renowned researcher. 🌟

 

Research Focus:

🔬 Dr. Alessandra Bitto’s research focus lies at the intersection of oxidative stress, inflammation, and therapeutic interventions for various health conditions. Her extensive body of work spans across multiple domains, including cardiovascular health, bone metabolism, and wound healing. With a particular emphasis on the effects of phytoestrogens, she has explored their potential in mitigating postmenopausal symptoms and managing metabolic syndrome. Additionally, her studies on erythropoietin’s angiogenic properties and the cholinergic anti-inflammatory pathway highlight her dedication to understanding the mechanisms underlying tissue repair and inflammation modulation. Dr. Bitto’s diverse research endeavors continue to shed light on novel therapeutic strategies for improving human health. 🔍🌱

Publication Top Notes:

  1. Oxidative stress: harms and benefits for human health 📚 Cited by 3403, 2017
  2. Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial 📚 Cited by 432, 2007
  3. ROS-mediated NLRP3 inflammasome activation in brain, heart, kidney, and testis ischemia/reperfusion injury📚 Cited by 409, 2016
  4. Recombinant human erythropoietin stimulates angiogenesis and wound healing in the genetically diabetic mouse 📚 Cited by 222, 2004
  5. Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: a two-year randomized, double-blind, placebo-controlled study 📚 Cited by 221, 2007
  6. Breast safety and efficacy of genistein aglycone for postmenopausal bone loss: a follow-up study📚 Cited by 217, 2008
  7. Effects of genistein on hot flushes in early postmenopausal women: a randomized, double-blind EPT-and placebo-controlled study. 📚 Cited by 210, 2004
  8. Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice 📚 Cited by 186, 2006
  9. Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats📚 Cited by 184, 2005
  10. Recombinant human erythropoietin improves angiogenesis and wound healing in experimental burn wounds 📚 Cited by 181, 2006