Chyi-Liang Chen | Molecular epidemiology | Best Researcher Award

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Prof. Chyi-Liang Chen | Molecular epidemiology | Best Researcher Award

Prof. Chyi-Liang Chen, Linkou Chang Gung Memorial Hospital Children’s Medical Center, Taiwan

🧬 Prof. Chyi-Liang Chen is an Associate Researcher at Chang Gung Memorial Hospital and the Department of Microbiology and Immunology, Chang Gung University, Taiwan. He earned his BSc, MSc, and PhD in Life Sciences from National Chung Hsing University. With extensive postdoctoral research at Chang Gung University and the University of Calgary, his expertise spans microbiology, molecular microbiology, protein engineering, bacterial genomics, and antimicrobial resistance. He has authored numerous SCIE-indexed publications on bacterial pathogenesis and genetic engineering. His work contributes to biotechnology, genomics, and patent applications, advancing microbial research. 🦠🔬📚

Publication Profile

Scopus

Orcid

🎓 Educational Background

Prof. Chyi-Liang Chen pursued his academic journey in Life Sciences at National Chung Hsing University, Taiwan. He obtained his Bachelor’s degree (1984–1988) from the Department of Life Sciences (formerly the Department of Botany). He then completed his Master’s degree (1988–1990) at the Institute of Life Sciences (previously the Institute of Botany Microbiome). Further advancing his expertise, he earned a Ph.D. (1990–1995) from the same institute. His strong foundation in microbiology, molecular biology, and botany has significantly contributed to his impactful research in bacterial genomics and biotechnology. 🧬🔬📖

🏅 Professional Experience

Prof. Chyi-Liang Chen has an extensive career in microbiology and immunology. He began as a Postdoctoral Fellow at Chang Gung University, Taiwan (1997–1999) before moving to the University of Calgary, Canada (1999–2002). He later returned to Chang Gung University (2002–2006). He served as an Assistant Professor at Yuanzhi University and later as an Assistant Researcher at Chang Gung Memorial Hospital (2006–2012). Since 2012, he has been an Associate Researcher at Chang Gung Memorial Hospital and, from 2022, also at the Department of Microbiology and Immunology, Chang Gung University. 🧪🔬📚

🔬 Research Focus

Prof. Chyi-Liang Chen specializes in infectious diseases, microbiology, and immunology. His research spans viral infections 🦠, antimicrobial resistance 💊, and host-pathogen interactions 🏥. He has contributed to studies on multiple viral infections in children, cytomegalovirus colitis, and antiviral treatments. His work also explores the gut microbiota’s role in cancer therapy and cross-species microRNAs. Additionally, he has investigated COVID-19 therapeutics 😷 and SARS-CoV-2 variants 🧬. His studies provide crucial insights into infectious disease management, making significant contributions to global health and microbiological research. 🌍🔍

Publication Top Notes

1️⃣ Multiple viral infections and antimicrobial use in hospitalized children with respiratory illness during pandemic and early post-pandemic era, Taiwan 🦠💊 (Heliyon, 2025) 
2️⃣ Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae 🧬🦠 (Journal of Microbiology, Immunology and Infection, 2025) 
3️⃣ Maternal Infections, Antibiotics, Steroid Use, and Diabetes Mellitus Increase Risk of Early-Onset Sepsis in Preterm Neonates 🤰🦠 (Pathogens, 2025) 
4️⃣ Adequate antiviral treatment lowers overall complications of cytomegalovirus colitis among inpatients with inflammatory bowel diseases 💊🦠 (BMC Infectious Diseases, 2024) – 2 citations
5️⃣ Gut microbiota and clinical response to immune checkpoint inhibitor therapy in patients with advanced cancer 🦠🧪 (Biomedical Journal, 2024) – 5 citations
6️⃣ Antimicrobial activity of eravacycline and other comparative agents on aerobic and anaerobic bacterial pathogens in Taiwan 💊🦠 (Journal of Global Antimicrobial Resistance, 2024) – 1 citation
7️⃣ Complete genome sequence of Bacillus halotolerans F29-3, a fengycin-producing strain 🧬🦠 (Microbiology Resource Announcements, 2024) 
8️⃣ Cytomegalovirus Diseases of the Gastrointestinal Tract in Immunocompetent Patients: A Narrative Review 🦠📖 (Viruses, 2024) – 5 citations
9️⃣ Safety, tolerability, and efficacy of intranasally-administered detoxified LTh(αK) in mild-to-moderate COVID-19 patients 💉🦠 (Human Vaccines and Immunotherapeutics, 2024) 
🔟 Worldwide SARS-CoV-2 Omicron variant infection: Emerging sub-variants and future vaccination perspectives 🦠💉 (Journal of the Formosan Medical Association, 2024) – 1 citation

Conclusion

Prof. Chyi-Liang Chen is highly suitable for the Best Researcher Award due to his strong academic background, international research experience, expertise in microbiology and bacterial pathogenesis, and high-impact publications. His work has significantly advanced molecular microbiology and biotechnology, making him a worthy candidate for this prestigious recognition.

Genetics and Molecular Biology

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Introduction of Genetics and Molecular Biology

Genetics and Molecular Biology are at the forefront of understanding the intricate machinery that governs life itself. This dynamic field investigates the genetic material and molecular processes underlying inheritance, development, evolution, and the molecular mechanisms of diseases. It is a cornerstone of modern biological research and holds the promise of unlocking the secrets of life’s blueprint.

Genome Sequencing and Analysis:

The study of entire genomes, from humans to microbes, has revolutionized our understanding of genetics. Researchers in this subfield explore the structure and function of genes, regulatory elements, and the role of non-coding DNA.

Genetic Variation and Population Genetics:

Investigating how genetic variations occur within populations and evolve over time is essential for understanding the diversity of life. This subtopic delves into the mechanisms of genetic diversity, adaptation, and speciation.

Epigenetics:

Epigenetics explores changes in gene expression that do not involve alterations to the DNA sequence itself. Researchers study how factors like DNA methylation and histone modification influence gene regulation, development, and disease.

Molecular Mechanisms of Disease:

In this subfield, scientists investigate the molecular basis of genetic disorders and diseases, from cancer to rare genetic conditions. Understanding the underlying mechanisms is crucial for developing targeted therapies.

Synthetic Biology:

Synthetic biology involves the design and construction of artificial biological systems for diverse applications, such as biofuel production or medical treatments. Researchers engineer biological components to create new functions and capabilities.

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