Yonggeun Hong | Neurophysiology | Excellence in Research

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Dr. Yonggeun Hong | Neurophysiology | Excellence in Research

Dr. Yonggeun Hong, Inje University, South Korea

👨‍🔬 Dr. Yonggeun Hong is a distinguished Professor and Director at Inje University, specializing in Biological Clock & Ageing Control. With a Ph.D. in Biochemistry and extensive global research experience, including at Harvard Medical School, he has led groundbreaking studies in areas like neuroscience and cardiovascular health. As Director of Research Centers, including RCAR and BPRC, he’s at the forefront of innovative aging research. His recent work focuses on quantifying neuronal cell-released hydrogen peroxide, employing advanced techniques like 3D mesoporous copper-enriched prussian blue microcubes. Dr. Hong’s contributions significantly advance our understanding of cellular mechanisms in aging and disease.

Publication profile:

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Education and Training:

🎓 Dr. Yonggeun Hong embarked on his academic journey at Gyeongsang National University in Jinju, Korea, where he earned his Bachelor of Science in Veterinary Medicine (D.V.M.) from 1988 to 1995. His passion for understanding biological mechanisms led him to pursue further studies, culminating in a Master of Science in Veterinary Physiology from 1995 to 1997, under the guidance of Dr. Joo-Heon Kim. This foundational education laid the groundwork for his subsequent endeavors.Driven by a desire to delve deeper into biochemical intricacies, Dr. Hong pursued a Ph.D. in Biochemistry from 1997 to 2001, with Dr. Yunbae Pak serving as his supervisor at Gyeongsang National University. This phase of his education equipped him with advanced research skills and a comprehensive understanding of cellular processes.Throughout his academic journey, Dr. Hong demonstrated a relentless pursuit of knowledge and a commitment to academic excellence. His diverse educational background in veterinary medicine, physiology, and biochemistry has uniquely positioned him as a multidisciplinary scholar, poised to make significant contributions to the field.

Professional Experiences:

👨‍🔬 Dr. Yonggeun Hong’s illustrious career spans various prestigious roles, reflecting his expertise and leadership in the field of biomedical research. Commencing as a Post-doctoral Research Scholar at the University of Iowa and later at the University of Texas Southwestern Medical Center, he honed his skills in Internal Medicine-Cardiology under the mentorship of Dr. Joseph A. Hill from 2001 to 2004. This foundational experience laid the groundwork for his subsequent endeavors.Transitioning into academia, Dr. Hong joined Inje University in Gimhae, Korea, where he has held multiple pivotal roles. As a Professor since 2004, he leads the Biological Clock & Ageing Control Lab within the Department of Physical Therapy & Rehabilitation, contributing significantly to both education and research. His commitment to advancing knowledge led to directorial positions at key research centers, including the Biohealth Products Research Center (BPRC) from 2014 to 2019 and the u-Healthcare & Anti-aging Research Center (u-HARC) from 2013 to 2015.His international collaborations further enriched his experience, evident during his tenure as a Research Associate at Harvard Medical School-Beth Israel Deaconess Medical Center from 2011 to 2013, under the supervision of Dr. Wenyi Wei, and as a Visiting Research Scholar from 2019 to 2021 in Internal Medicine-Onc/Hem. Presently, as Director of the Research Center for Aged-life Redesign (RCAR) at Inje University, Dr. Hong continues to spearhead innovative research initiatives aimed at understanding and addressing the complexities of aging.

Research Focus:

🔬 Dr. Yonggeun Hong’s research focus revolves around elucidating the intricate mechanisms underlying aging, neurodegenerative diseases, and cancer therapeutics. With a particular emphasis on autophagy, apoptosis, and senescence, his work explores the interplay of cellular processes in conditions such as colorectal cancer and spinal cord injury. Through innovative studies on melatonin treatment, exercise-based neurorehabilitative therapy, and the modulation of insulin/IGF signaling, he aims to uncover novel therapeutic strategies for enhancing neural reconstruction and functional recovery. Dr. Hong’s multifaceted investigations integrate molecular, cellular, and translational approaches to advance our understanding and treatment of age-related disorders and neurological conditions. 🧠🔬

Publication Top Notes:

  1. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1– Cited by 10285, 2021 📑
  2. Therapeutic implications for overcoming radiation resistance in cancer therapy – Cited by 220, 2015 🎯
  3. Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells – Cited by 138, 2014 🌿
  4. The effects of smartphone use on upper extremity muscle activity and pain threshold – Cited by 137, 2015 📱
  5. Differential gene expression patterns in porcine nuclear transfer embryos reconstructed with fetal fibroblasts and mesenchymal stem cells – Cited by 123, 2007 🐖
  6. Pathophysiological and neurobehavioral characteristics of a propionic acid-mediated autism-like rat model – Cited by 115, 2018 🧠
  7. Implication of mouse Vps26b–Vps29–Vps35 retromer complex in sortilin trafficking – Cited by 73, 2010 🐭
  8. Molecular and functional interaction of the myokine irisin with physical exercise and Alzheimer’s disease– Cited by 71, 2018 💪
  9. Melatonin plus exercise‐based neurorehabilitative therapy for spinal cord injury– Cited by 69, 2010 🌙
  10. Neurocognitive effects of melatonin treatment in healthy adults and individuals with Alzheimer’s disease and insomnia: a systematic review and meta-analysis of randomized … – Cited by 57, 2021 🧠