Ching-Chuan Kuo | Cancer Pharmacology | Best Researcher Award

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Prof. Dr. Ching-Chuan Kuo | Cancer Pharmacology | Best Researcher Award

Prof. Dr. Ching-Chuan Kuo, National Health Research Institutes, Taiwan

๐ŸŽ“ Prof. Dr. Ching-Chuan Kuo earned her Ph.D. in food chemistry and nutraceutical functionality from National Taiwan University. She is an Investigator at the National Health Research Institutes (NHRI) and a Professor at the Biotechnology Center, National Chung Hsing University. ๐Ÿ”ฌ Her research focuses on cancer biology, experimental therapeutics, precision medicine, and translational research. Key contributions include developing four cancer drug candidates that achieved US and Taiwan FDA IND approvals. ๐Ÿ“š Dr. Kuo has authored 108 SCI articles with 5,153 citations, an H-index of 48, and holds two patents. Her work has transformed cancer treatment and precision therapeutics. ๐Ÿงฌ

 

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Education Background ๐ŸŽ“

Prof. Dr. Ching-Chuan Kuo completed her Ph.D. in Nutritional Biochemistry and Natural Product Chemistry at the Institute of Food Science and Technology, College of Bioresources and Agriculture, National Taiwan University, Taipei, Taiwan, from September 1995 to July 2001. ๐ŸŒฑ Her doctoral research laid the foundation for her distinguished career in cancer biology and experimental therapeutics, blending the fields of food chemistry and biotechnology. Her strong academic background in biochemistry and natural products has driven her groundbreaking work in drug discovery and cancer treatment. ๐Ÿ“˜ This education has been crucial in her continued success and innovations in translational medicine. ๐Ÿงฌ

 

Professional Experience ๐Ÿ’ผ

Prof. Dr. Ching-Chuan Kuo has held various prestigious positions throughout her career. Since August 2022, she has been a jointly appointed Professor at the Biotechnology Center, National Chung Hsing University, Taiwan. ๐ŸŒฑ In January 2022, she became an Investigator at the Institute of Biotechnology and Pharmaceutical Research, NHRI, after serving as an Associate Investigator from 2013 to 2021. ๐Ÿ”ฌ Dr. Kuoโ€™s journey began in 2001 as a Postdoctoral Fellow at the Division of Cancer Research, NHRI, followed by roles as a Research Associate and Assistant Investigator at the National Institute of Cancer Research. Her extensive career reflects her expertise and dedication to advancing cancer research. ๐Ÿงฌ

 

Research Interests ๐Ÿ”ฌ

Prof. Dr. Ching-Chuan Kuoโ€™s research focuses on several key areas within cancer biology. Her work involves the identification and validation of novel oncotargets, the development of clinically relevant tumor models, and the discovery of new anticancer drugs. ๐Ÿ’ก She also explores cancer pharmacology and experimental therapeutics, aiming to improve cancer treatment. Her research extends to understanding chemo- and radio-resistance mechanisms and discovering strategies to overcome them. ๐Ÿงฌ Additionally, Prof. Kuo is deeply invested in precision medicine and translational research, seeking to bridge the gap between laboratory findings and clinical applications to enhance cancer therapies. ๐ŸŒฑ

 

Publication Top Notes

  • Cytotoxic triterpenes from the aerial roots of Ficus microcarpa – 259 citations, 2005 ๐Ÿ“š๐Ÿƒ
  • BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells – 259 citations, 2004 ๐Ÿงช๐Ÿ’ฅ
  • Effects of drying and extrusion on colour, chemical composition, antioxidant activities and mitogenic response of sweet potatoes – 196 citations, 2009 ๐Ÿ ๐Ÿ”ฌ
  • 4-Ketopinoresinol, a novel naturally occurring ARE activator – 142 citations, 2012 ๐ŸŒฑ๐Ÿ’ช
  • Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge – 137 citations, 2004 ๐ŸŒฟ๐Ÿ”ฌ
  • 2,2โ€˜-Diphenyl-1-picrylhydrazyl Radical-Scavenging Active Components from Adlay – 137 citations, 2002 ๐ŸŒพ๐Ÿงช
  • Surface ฮฑ-enolase promotes extracellular matrix degradation and tumor metastasis – 136 citations, 2013 ๐Ÿงฌ๐Ÿ™๏ธ
  • Antagonism of free-radical-induced damage of adlay seed – 111 citations, 2001 ๐ŸŒฑ๐Ÿ”ฌ
  • Scaffold-hopping strategy: synthesis and biological evaluation of 5, 6-fused bicyclic heteroaromatics – 107 citations, 2011 ๐Ÿงฌ๐Ÿ”ฌ
  • Synthesis and evaluation of 3-aroylindoles as anticancer agents – 107 citations, 2009 ๐Ÿ’Š๐Ÿ”ฌ
  • 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents – 106 citations, 2006 ๐Ÿงช๐Ÿ’ก
  • Four new 6-nor-5 (6โ†’ 7) abeo-abietane type diterpenes from the bark of Taiwania cryptomerioides – 103 citations, 2005 ๐ŸŒฒ๐Ÿ”ฌ

 

 

Ammu Kutty Radhakrishnan | Cancer Immunology | Best Researcher Award

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Prof. Ammu Kutty Radhakrishnan | Cancer Immunology | Best Researcher Award

Prof. Ammu Kutty Radhakrishnan, Monash University Malaysia, Malaysia

 

Prof. Ammu Kutty Radhakrishnan is a distinguished immunologist with a PhD from the University of Cambridge (1994), an MSc in Biochemistry (1990), and a BSc (First Class Honours) from the University of Malaya (1987). Currently, a Professor of Immunology at Monash University Malaysia, she has over 25 years of academic leadership and research experience. Prof. Ammu specializes in immunotherapy and food as medicine research, serving as Head of this research strength. Her career spans significant roles at International Medical University and Oxford. She is a research consultant, active in COVID-19 vaccine efforts, and supervises PhD and MSc students. ๐ŸŒฟ๐Ÿงฌ๐Ÿ“š

 

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Academic Excellence

Prof. Ammu Kutty Radhakrishnan has an exceptional academic background, with a PhD in Immunology from the University of Cambridge (1994) and degrees in Biochemistry from the University of Malaya. Her education forms a solid foundation for her expertise in immunology and biomedical sciences, contributing to her distinguished career.

Professional Experience

Prof. Radhakrishnan has held key roles, such as Professor at Monash University Malaysia and the International Medical University (IMU). Her leadership in academic programs, such as head of the Food as Medicine Research Strength and chief examiner roles, showcases her commitment to advancing education and research.

Research Contributions

Prof. Radhakrishnan has supervised numerous PhD and Masterโ€™s students, guiding 39 doctoral and 20 masterโ€™s research projects to completion. Her extensive research supervision experience highlights her dedication to fostering scientific inquiry and innovation. Additionally, her collaborative efforts with industry partners demonstrate her ability to apply research to real-world problems.

Conclusion

Prof. Ammu Kutty Radhakrishnanโ€™s outstanding academic credentials, extensive research supervision, leadership roles, and global health contributions, she is an ideal candidate for the Best Researcher Award. Her work in immunology, biomedicine, and collaboration with industry partners demonstrates her excellence in both academic and applied research, making her a worthy contender for this prestigious recognition.

 

Publication Top Notes ย 

  • Protective effect of aqueous extract from Spirulina platensis against cell death induced by free radicals (2010) โ€“ 292 citations ๐Ÿงช
  • Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59 (1994) โ€“ 259 citations ๐Ÿงฌ
  • Rind of the rambutan, Nephelium lappaceum, a potential source of natural antioxidants (2008) โ€“ 193 citations ๐Ÿ‡
  • Current concepts of neurodegenerative mechanisms in Alzheimerโ€™s disease (2018) โ€“ 176 citations ๐Ÿง 
  • Bioactive Compounds: Natural Defense Against Cancer? (2019) โ€“ 169 citations ๐ŸŒฟ
  • Protective mechanisms of flavonoids in Parkinsonโ€™s disease (2015) โ€“ 162 citations ๐Ÿง‘โ€โš•๏ธ
  • Tocotrienol research: past into present (2012) โ€“ 157 citations ๐ŸŒฐ
  • Standardised Mangifera indica extract is an ideal antioxidant (2009) โ€“ 149 citations ๐Ÿฅญ
  • Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson’s disease (2020) โ€“ 128 citations ๐Ÿš€
  • Tocotrienol-rich fraction from palm oil affects gene expression in tumors resulting from MCF-7 cell inoculation in athymic mice (2004) โ€“ 126 citations ๐Ÿงซ
  • Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity (2013) โ€“ 124 citations ๐Ÿงช