Oleg Shatursky | Toxinology Award | Best Researcher Award

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Dr. Oleg Shatursky | Toxinology Award | Best Researcher Award

Dr. Oleg Shatursky, Palladin Institute of Biochemistry, National Academy of Science of Ukraine, Ukraine

Dr. Oleg Shatursky 🧪, DSc in biochemistry, is a distinguished researcher renowned for his expertise in investigating pore-forming proteins in bilayer lipid membranes. With a career spanning across Ukraine, Australia, and the USA, his work has significantly advanced the understanding of ion channel formation and membrane interactions. Notable achievements include elucidating the mechanisms of toxins from black widow spiders and Clostridium perfringens. Shatursky’s contributions are marked by numerous publications and prestigious honors, including the Soros Foundation Award for Science. His dedication to scientific inquiry continues to inspire the field of biochemistry. 🌐

 

Publication Profile

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Professional Journey 🚀

Dr. Oleg Shatursky’s illustrious career in biochemistry began with a Bachelor’s degree from Kiev State University, where he explored the ion-conductive properties of bilayer lipid membranes for his graduation paper. His path led him to the Palladin Institute of Biochemistry, where he served as a Research Assistant under Prof. M.D. Kursky. Dr. Shatursky pursued his Ph.D. at the same institute, delving into the intricacies of membrane modification. His academic pursuits took him abroad for postdoctoral positions in Australia and the USA, shaping his expertise in muscle biochemistry. Returning to Ukraine, he assumed senior and leading research roles, focusing on neurochemistry and advancing scientific frontiers.

 

Honours and Awards 🏅

In 1993, Dr. Oleg Shatursky was honored with the prestigious Soros Foundation Award for Science, a testament to his outstanding contributions to bio

Research Focus

Dr. Oleg Shatursky’s research focus revolves around elucidating the intricate mechanisms of pore-forming toxins and their interactions with lipid bilayer membranes. Through extensive studies spanning various toxins, including cholesterol-dependent cytolysins and alpha-latrotoxin, he investigates the formation of ion channels and their impact on cellular physiology. His work sheds light on fundamental processes such as membrane insertion and pore assembly, offering novel insights into toxin-induced cellular responses. Dr. Shatursky’s dedication to understanding these complex phenomena advances our knowledge of membrane biology and holds implications for therapeutic interventions. 🧪

Publication Top Notes

📚 Publication: The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins cited 429 times, published in 1999.
🔬 Publication: “The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane β-hairpins cited 218 times, published in 2000.
🦠 Publication: Clostridium perfringens Beta-Toxin Forms Potential-Dependent, Cation-Selective Channels in Lipid Bilayers cited 106 times, published in 2000.
🧠 Publication: “Monoclonal antibodies can uncouple the main α-latrotoxin effects: toxin-induced Ca2+ influx and stimulated neurotransmitter release cited 28 times, published in 1993.
🕷️ Publication: Interaction of α-latroinsectotoxin from Latrodectus mactans venom with bilayer lipid membranescited 25 times, published in 1995.
🧪 Publication: “Vitamin B1 thiazole derivative reduces transmembrane current through ionic channels formed by toxins from black widow spider venom and sea anemone in planar phospholipid membranes cited 21 times, published in 2007.
🔍 Publication: Long open amphotericin channels revealed in cholesterol-containing phospholipid membranes are blocked by thiazole derivative” cited 15 times, published in 2014.
🩸 Publication: “Membrane action of polyhexamethylene guanidine hydrochloride revealed on smooth muscle cells, nerve tissue and rat blood platelets: A biocide driven pore-formation in …” cited 14 times, published in 2019.
🧫 Publication: “Anion carrier formation by calix [4] arene-bis-hydroxymethylphosphonic acid in bilayer membranes” cited 14 times, published in 2014.
🔍 Publication: “Probing the structure-function relationship of α-latrotoxin-formed channels with antibodies and pronase” cited 9 times, published in 1996.