Prof. Dr. Alaa M. Hayallah, Assiut University & Faculty of Pharmacy Dean, Sphinx University, Egypt
Prof. Dr. Alaa M. Hayallah is a distinguished pharmaceutical scientist with a B.Sc. in Pharmaceutical Sciences from Assiut University, Egypt (honors). He earned an M.Sc. in Pharmaceutical Organic Chemistry, specializing in synthesizing thiazolo[3,2-a]benzimidazole derivatives with hypoglycemic potential. He has held numerous leadership roles, including Vice Dean and Head of the Pharmaceutical Organic Chemistry Department at Deraya University, Egypt (2015-2019). Prof. Hayallah contributed to quality assurance initiatives at Esraa University, Jordan, and Sphinx University, Egypt. His work emphasizes education, research, and development in pharmaceutical sciences. ππ¬
Publication Profile
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Academic Background
Born on June 28, 1967, in Egypt, Prof. Dr. Alaa M. Hayallah is a renowned pharmaceutical scientist. He earned his B.Sc. in Pharmaceutical Sciences with honors and later completed a Ph.D. in Pharmaceutical Organic Chemistry. His groundbreaking doctoral research focused on the design, synthesis, and biological evaluation of compounds targeting A2B adenosine receptors. Prof. Hayallah is multilingual, fluent in Arabic, English, and German, and has gained extensive international experience during his academic journey, particularly through studies and research in Germany. His work exemplifies excellence in pharmaceutical innovation and education. π§ͺπ
Research Experience
Prof. Dr. Alaa M. Hayallah has extensive research experience, supervised by esteemed professors at Assiut University, Egypt, and Bonn University, Germany. His Ph.D. focused on designing and synthesizing A2B selective adenosine receptor antagonists as potential immunomodulators under the guidance of Prof. Dr. Christa E. MΓΌller. He has mastered pharmaceutical organic synthesis techniques, including thiazolo[3,2-a]benzimidazole derivatives and spectroscopic analysis (IR, NMR, MS). Prof. Hayallah regularly participated in radiopharmacy, clinical pharmacy, and radiation safety courses. His contributions include hypoglycemic agent investigations and aromatic compound synthesis. He actively engaged in international conferences and workshops to enhance his expertise. π§ͺπβ¨
Achievements and Interests
Prof. Dr. Alaa M. Hayallah has earned notable recognition throughout his career. He served as Chairman of the Assiut Pharmacists Syndicate (2006-2007), Vice President of the International Operation Smile Committee in Assiut, and Vice President of the Medical Professions Union Committee in Assiut. Beyond his professional accomplishments, Prof. Hayallah has diverse interests, including music, computer technology, and football, which reflect his multifaceted personality. His dedication to both his professional responsibilities and personal passions highlights his holistic approach to life and career. πβ¨
Research Focus
Prof. Dr. Alaa M. Hayallah’s research spans pharmaceutical organic chemistry, with a focus on designing and synthesizing biologically active compounds. His contributions include selective adenosine receptor antagonists, apoptotic antitumor agents, and EGFR inhibitors. He explores anti-inflammatory, anticancer, antibacterial, and bronchodilator therapies, combining medicinal chemistry with advanced techniques like docking studies and ADME analysis. His work extends to nanocomposites for molecular sensing and versatile organic syntheses. With over two decades of impactful research, his studies integrate cutting-edge chemistry and biology, addressing diverse therapeutic targets and advancing drug discovery. ππ¬β¨
Publication Top Notes
- 𧬠Slit2βRobo4 signalling promotes vascular stability by blocking Arf6 activity β Nature Cell Biology (2009), cited by 265.
- π Antinociceptive effects of novel A2B adenosine receptor antagonists β Journal of Pharmacology and Experimental Therapeutics (2004), cited by 181.
- π§ͺ 1,8-Disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists β Journal of Medicinal Chemistry (2002), cited by 175.
- 𧫠EGFR inhibitors and apoptotic inducers: Design, synthesis, anticancer activity, and docking studies of novel xanthine derivatives β Bioorganic Chemistry (2019), cited by 127.
- π¬ Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents β European Journal of Medicinal Chemistry (2019), cited by 78.
- π‘οΈ Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia β Naunyn-Schmiedeberg’s Archives of Pharmacology (2008), cited by 68.
- π± Recent progress in biologically active indole hybrids: A mini review β Pharmacological Reports (2022), cited by 62.
- 𧬠A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists β Journal of Medicinal Chemistry (2006), cited by 59.
- 𧩠Click chemistry synthesis, biological evaluation, and docking study of some novel 2β²-hydroxychalcone-triazole hybrids as potent anti-inflammatory agents β Bioorganic Chemistry (2020), cited by 55.
- π¬οΈ Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities β Archives of Pharmacal Research (2011), cited by 55.
Conclusion
Prof. Dr. Alaa M. Hayallahβs extensive academic achievements, leadership roles, and impactful research contributions make him a strong candidate for the Best Researcher Award. His work exemplifies innovation and dedication to advancing pharmaceutical sciences.